tradmap

SEPN Septerna, Inc.

$43.25 -1.53%

Data as of close

Healthcare · Pharmaceutical Preparations

Septerna, Inc. (SEPN) is a healthcare company in the Pharmaceutical Preparations industry, with a market capitalization of $2.0 billion. Shares last traded at $43.25, 15.4% below their 52-week high. Over the past year the stock is up 101.3%. Net profit margin is -24.5%, below the peer median of -7.6%. Revenue grew 4174.5% year over year.

Market Cap
$2.0B
Shares Out
46.7M
EPS (TTM)
-$0.53
P/E (TTM)*
—
P/S Ratio
20.42
P/B Ratio
5.22
Dividend / Share
—
Dividend Yield
—
52-Week High
$51.10
52-Week Low
$17.65
Volume (venue)
34,506
Avg Vol (3m, venue)
22,381.889

* P/E (TTM) = market cap ÷ net income over the trailing twelve months where four consecutive quarters are reported, otherwise the latest fiscal year — the same basis as the peer table and the screener, so it can differ from price ÷ EPS.

Performance

1W
+4.49%
1M
+14.65%
3M
+11.01%
6M
+74.25%
YTD
+55.35%
1Y
+101.26%

Daily candles · volume · SMA(20)/SMA(50) · Databento EQUS.MINI.

Technicals

RSI (14)
61.85
SMA (50)
$39.01
SMA (200)
$32.15
Price vs SMA50
+10.87%
Price vs SMA200
+34.51%
ATR (14)
$2.10

Full technical analysis (26 indicators, D/W/M) →

Financials

Revenue
$99M
Net Income
-$24M
Gross Margin
—
Operating Margin
-44.0%
Net Margin
-24.5%
Return on Equity
-6.3%
Return on Assets
-4.3%
Current Ratio
4.99
Debt / Equity
0.47
Revenue Growth (YoY)
+4174.5%

Trailing twelve months where four consecutive quarters are reported, otherwise the latest fiscal year; revenue is the fiscal-year figure where quarterly revenue covers under half of it (typical for banks, insurers and REITs), and margins are taken on it; latest reported period ends 2026-06-30. Source: SEC EDGAR/XBRL.

Full financials — revenue, cash flow & debt over time →

Recent earnings

PeriodEPS (diluted)Reported
Q2 2026 -$0.29 2026-08-10
Q1 2026 -$0.19 2026-05-11
Q4 2025 (derived) -$0.23 2026-03-09
FY 2025 -$1.10 2026-03-09
Q3 2025 $0.18 2025-11-10
Q2 2025 -$0.56 2025-08-11

Q4 marked "derived" = fiscal-year EPS minus Q1–Q3 (10-Ks report only the annual figure); EPS is not strictly additive, so it can differ by a cent or two from the issuer's own Q4.

Full earnings history →

Pharmaceutical Preparations peers

SEPN vs 14 industry peers (Pharmaceutical Preparations), by market cap. Data as of close

P/S vs peers
20.42 / 7.81 med
+161% premium
Net margin vs peers
-24.5% / -7.6% med
below median
1–14 of 14
LLYLilly (Eli)$1.33T48.1315.3531.9%-0.28%
JNJJohnson & Johnson$652.2B40.526.5716.2%-0.82%
ONCBeone Medicines Ltd.$533.8B814.0587.0910.7%-2.48%
ABBVAbbVie$510.3B80.877.939.8%-2.05%
MRKMerck$366.4B115.465.504.8%-0.22%
ABTAbbott Laboratories$192.1B30.614.2613.9%+3.81%
PFEPfizer$175.0B40.412.756.8%+0.69%
VRTXVertex Pharmaceuticals$144.5B32.8011.4835.0%+1.96%
BMYBristol Myers Squibb$128.8B13.942.5818.5%+0.90%
REGNRegeneron Pharmaceuticals$99.4B20.645.8928.5%+3.63%
TEVATeva Pharmaceutical Industries Ltd$47.4B67.142.744.1%-3.35%
ZTSZoetis$34.4B13.143.6127.5%+4.35%
RPRXRoyalty Pharma Plc$29.6B36.3511.6832.1%-0.98%
ROIVRoivant Sciences Ltd.$25.9B—3441.87—-2.76%

Source: SEC EDGAR (fundamentals/EPS/dividends) · Databento EQUS.MINI (prices) · market cap & yield computed by tradmap. Informational only — not financial advice.