6 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has grown 70.7% per year over the past 5 years.
Operating margin has expanded, at 8.5% in the latest year.
Financial health
Total debt ($220M) exceeds cash ($111M); net debt is $109M.
Total debt has grown slower than revenue (20.4% vs 70.7% per year).
Operating income covered interest expense 0.9× in the latest year.
Total debt is 8.4× EBITDA.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
2025
$292M
$554000
0.0%
8.5%
4.0%
0.1%
—
$220M
$111M
2024
$203M
-$55M
0.0%
-16.6%
185.2%
-17.0%
—
$232M
$72M
2023
$164M
-$62M
0.0%
-26.8%
917.9%
-19.3%
—
$191M
$67M
2022
$110M
-$95M
0.0%
-74.3%
-209.5%
-27.5%
—
$187M
$122M
2021
$50M
-$123M
0.0%
-232.2%
-128.9%
-40.3%
-$97M
$88M
$67M
2020
$20M
-$91M
0.0%
-414.5%
-270.0%
-57.3%
-$81M
$87M
$38M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
Mar '26
$83M
$2M
0.0%
9.5%
17.2%
0.6%
—
$221M
$112M
Dec '25
$86M
$11M
0.0%
19.5%
80.9%
2.9%
—
$220M
$111M
Sep '25
$74M
$621000
0.0%
9.0%
-72.1%
0.2%
—
$219M
$92M
Jun '25
$72M
-$2M
0.0%
6.3%
10.0%
-0.6%
—
$219M
$59M
Mar '25
$60M
-$9M
0.0%
-5.1%
26.2%
-2.9%
—
$230M
$58M
Dec '24
$60M
-$5M
0.0%
2.8%
17.3%
-1.6%
—
$232M
$72M
Sep '24
$54M
-$16M
0.0%
-23.8%
55.6%
-4.9%
—
$216M
$59M
Jun '24
$48M
-$15M
0.0%
-17.0%
77.8%
-4.5%
—
$230M
$58M
Mar '24
$41M
-$19M
0.0%
-35.1%
206.8%
-5.6%
—
$230M
$63M
Dec '23
$44M
-$13M
0.0%
-22.2%
197.4%
-4.2%
—
$191M
$67M
Sep '23
$48M
-$12M
0.0%
-10.2%
-315.4%
-3.7%
—
$190M
$46M
Jun '23
$38M
-$20M
0.0%
-42.0%
-145.5%
-6.0%
—
$188M
$46M
Mar '23
$33M
-$17M
0.0%
-40.0%
-56.0%
-5.2%
—
$188M
$51M
Dec '22
$33M
-$13M
0.0%
-45.8%
-28.6%
-3.8%
—
$187M
$122M
Sep '22
$30M
-$22M
0.0%
-63.2%
-39.7%
-7.2%
—
$139M
$84M
Jun '22
$25M
-$26M
0.0%
-74.7%
-35.4%
-8.2%
—
$138M
$95M
Mar '22
$22M
-$34M
0.0%
-131.7%
-35.0%
-10.0%
—
$138M
$104M
Dec '21
$21M
-$51M
0.0%
-225.3%
-53.3%
-16.7%
-$29M
$88M
$67M
Sep '21
$11M
-$26M
70.9%
-220.2%
1056.8%
-19.8%
—
$88M
$59M
Jun '21
$9M
-$28M
0.0%
-289.5%
-138.3%
—
—
—
—
Valuation over time
How the market has priced XERS against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-earnings ratio has risen from 2599.9× (Dec '25) to 2823.7× (Sep '26).
The price-to-sales ratio has risen from 2.7× (Mar '23) to 5.4× (Sep '26).
Price / earnings (P/E)
P/E
Price / sales (P/S)
P/S
Frequently asked questions
Is XERS growing its revenue and profit?
Over the past 5 years, Xeris Biopharma Holdings, Inc.'s revenue has grown 70.7% per year. These are computed facts, not advice.
How much debt does XERS have?
As of FY2025, Xeris Biopharma Holdings, Inc. reported $220M of total debt against $111M of cash; operating income covered interest expense 0.9×.
What is XERS's profit margin?
In FY2025, gross margin was —, operating margin 8.5%, and net margin 0.2%.
What is XERS's P/E ratio?
As of Sep '26, Xeris Biopharma Holdings, Inc. traded at a price-to-earnings ratio of about 2823.7× (market cap ÷ latest annual net income). The valuation charts above show how its P/E, P/S have moved with the share price. These are computed facts, not advice.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.