UPB Upstream Bio, Inc.
$6.24 +1.55%
Healthcare · Pharmaceutical Preparations
Upstream Bio, Inc. (UPB) is a healthcare company in the Pharmaceutical Preparations industry, with a market capitalization of $339 million. Shares last traded at $6.24, 81.5% below their 52-week high. Over the past year the stock is down 39.3%.
Market Cap
$339M
Shares Out
54.4M
EPS (TTM)
$-4.39
P/E Ratio
—
P/S Ratio
—
P/B Ratio
—
Dividend / Share
—
Dividend Yield
—
52-Week High
$33.69
52-Week Low
$5.86
Volume
65,761
Avg Vol (3m)
38,958.444
Performance
1W
-2.27%
1M
-22.26%
3M
-25.55%
6M
-78.73%
YTD
-76.96%
1Y
-39.29%
Chart
Full chart →Daily candles · volume · SMA(20)/SMA(50) · Databento EQUS.MINI.
Technicals
RSI (14)
32.86
SMA (50)
$8.50
SMA (200)
$17.58
Price vs SMA50
-26.65%
Price vs SMA200
-64.53%
ATR (14)
$0.47
Recent earnings
| Period | EPS (diluted) | Reported |
|---|---|---|
| Q1 2026 | $-0.75 | 2026-05-13 |
| FY 2025 | $-2.66 | 2026-03-26 |
| Q3 2025 | $-1.88 | 2025-11-05 |
| Q2 2025 | $-1.25 | 2025-08-06 |
| Q1 2026 | $-0.51 | 2026-05-13 |
| FY 2025 | $-5.58 | 2026-03-26 |
Pharmaceutical Preparations peers
UPB vs 14 industry peers (Pharmaceutical Preparations), by market cap.
1–14 of 14
| LLY | Lilly (Eli) | $1.04T | 50.16 | 15.88 | 31.7% | -1.17% |
| JNJ | Johnson & Johnson | $549.8B | 20.51 | 5.84 | 28.5% | -2.42% |
| ONC | Beone Medicines Ltd. | $390.6B | 1361.26 | 73.10 | 5.4% | +2.83% |
| ABBV | AbbVie | $382.5B | 90.51 | 6.25 | 6.9% | -2.16% |
| MRK | Merck | $281.6B | 15.43 | 4.33 | 28.1% | -1.30% |
| ABT | Abbott Laboratories | $154.3B | 23.65 | 3.48 | 14.7% | +0.09% |
| PFE | Pfizer | $143.7B | 18.50 | 2.30 | 12.4% | -2.89% |
| VRTX | Vertex Pharmaceuticals | $114.6B | 28.99 | 9.55 | 32.9% | -1.63% |
| BMY | Bristol Myers Squibb | $110.3B | 15.63 | 2.29 | 14.6% | -2.35% |
| REGN | Regeneron Pharmaceuticals | $63.4B | 14.08 | 4.42 | 31.4% | +0.38% |
| ALNY | Alnylam Pharmaceuticals | $36.9B | 117.57 | 9.93 | 8.4% | -1.66% |
| TEVA | Teva Pharmaceutical Industries Ltd | $36.6B | 25.98 | 2.12 | 8.2% | -3.33% |
| ZTS | Zoetis | $33.1B | 12.37 | 3.49 | 28.2% | +2.09% |
| RPRX | Royalty Pharma Plc | $23.1B | 30.02 | 9.73 | 32.4% | -1.30% |
Source: SEC EDGAR (fundamentals/EPS/dividends) · Databento EQUS.MINI (prices) · market cap & yield computed by tradmap. Informational only — not financial advice.