SYRE Spyre Therapeutics, Inc.
$87.25 +0.21%
Updated
Healthcare · Pharmaceutical Preparations
Spyre Therapeutics, Inc. (SYRE) is a healthcare company in the Pharmaceutical Preparations industry, with a market capitalization of $7.7 billion. Shares last traded at $87.25, 20.8% below their 52-week high. Over the past year the stock is up 419.2%.
Market Cap
$7.7B
Shares Out
88.2M
EPS (TTM)
$-4.16
P/E Ratio
—
P/S Ratio
—
P/B Ratio
6.99
Dividend / Share
—
Dividend Yield
—
52-Week High
$110.21
52-Week Low
$14.63
Volume
70,491
Avg Vol (3m)
78,322.254
Performance
1W
-6.77%
1M
-16.34%
3M
+11.23%
6M
+115.01%
YTD
+184.85%
1Y
+419.19%
Chart
Full chart →Daily candles · volume · SMA(20)/SMA(50) · Databento EQUS.MINI.
Technicals
RSI (14)
32.84
SMA (50)
$97.82
SMA (200)
$61.59
Price vs SMA50
-10.81%
Price vs SMA200
+41.67%
ATR (14)
$5.12
Financials
Revenue
$0M
Net Income
$-179M
Gross Margin
—
Operating Margin
—
Net Margin
—
Return on Equity
-16.2%
Return on Assets
-15.3%
Current Ratio
18.53
Debt / Equity
0.07
Revenue Growth (YoY)
—
Latest reported annual period ending 2026-06-30 · SEC EDGAR/XBRL.
Recent earnings
| Period | EPS (diluted) | Reported |
|---|---|---|
| Q2 2026 | $-1.09 | 2026-08-04 |
| Q1 2026 | $-0.74 | 2026-05-05 |
| Q3 2025 | $-1.24 | 2025-11-04 |
| Q2 2025 | $-1.09 | 2025-08-05 |
| Q3 2024 | $-3.43 | 2024-11-07 |
| Q2 2024 | $-2.02 | 2024-08-07 |
Pharmaceutical Preparations peers
SYRE vs 14 industry peers (Pharmaceutical Preparations), by market cap. Updated
1–14 of 14
| LLY | Lilly (Eli) | $1.09T | 40.86 | 13.70 | 33.5% | -0.02% |
| JNJ | Johnson & Johnson | $670.6B | 31.88 | 6.85 | 21.5% | +1.04% |
| ONC | Beone Medicines Ltd. | $535.9B | 817.25 | 87.43 | 10.7% | +0.23% |
| ABBV | AbbVie | $459.8B | 72.87 | 7.14 | 9.8% | -0.57% |
| MRK | Merck | $375.8B | 118.44 | 5.65 | 4.8% | +0.44% |
| ABT | Abbott Laboratories | $189.5B | 30.20 | 4.20 | 13.9% | -1.50% |
| PFE | Pfizer | $164.2B | 37.91 | 2.58 | 6.8% | -0.76% |
| VRTX | Vertex Pharmaceuticals | $141.5B | 32.11 | 11.24 | 35.0% | +0.24% |
| BMY | Bristol Myers Squibb | $139.1B | 14.98 | 2.83 | 18.9% | +0.62% |
| REGN | Regeneron Pharmaceuticals | $87.2B | 20.15 | 5.61 | 27.9% | -1.02% |
| TEVA | Teva Pharmaceutical Industries Ltd | $42.6B | 60.41 | 2.46 | 4.1% | -2.32% |
| ALNY | Alnylam Pharmaceuticals | $35.4B | 43.77 | 9.52 | 21.8% | -1.10% |
| ZTS | Zoetis | $31.5B | 12.05 | 3.31 | 27.5% | +0.16% |
| RPRX | Royalty Pharma Plc | $28.2B | 34.56 | 11.11 | 32.1% | +1.24% |
Source: SEC EDGAR (fundamentals/EPS/dividends) · Databento EQUS.MINI (prices) · market cap & yield computed by tradmap. Informational only — not financial advice.