5 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has declined 68.7% per year over the past 4 years.
Operating margin has contracted, at -312631.8% in the latest year.
Financial health
The company is unprofitable and has less than a year of cash runway at its current free-cash-flow burn.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
2025
$22000
-$61M
0.0%
-312631.8%
-1099.3%
-119.9%
-$44M
—
$16M
2024
$0
-$53M
—
—
-205.8%
-54.0%
-$41M
—
$48M
2023
$2M
-$71M
0.0%
-4687.9%
-106.2%
-59.5%
-$64M
—
$36M
2022
$3M
-$58M
0.0%
-1889.3%
-45.7%
-32.2%
-$76M
—
$58M
2021
$2M
-$4M
0.0%
-168.7%
3.5%
-4.0%
-$7M
—
$56M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
Jun '26
$17000
-$13M
0.0%
-85229.4%
374.9%
-38.5%
—
—
$6M
Mar '26
$16000
-$4M
0.0%
-28850.0%
-164.6%
-11.0%
—
—
$9M
Dec '25
—
-$14M
—
—
-258.8%
-28.2%
-$7M
—
$16M
Sep '25
—
-$18M
—
—
-223.2%
-34.4%
-$9M
—
$12M
Jun '25
$0
-$15M
—
—
-59.8%
-21.5%
-$13M
—
$22M
Mar '25
$0
-$14M
—
—
-37.3%
-17.0%
-$14M
—
$34M
Dec '24
$0
-$610000
—
—
-2.4%
-0.6%
-$14M
—
$48M
Sep '24
$0
-$29M
—
—
-180.5%
-50.0%
-$8M
—
$10M
Jun '24
$0
-$11M
—
—
-25.4%
-12.9%
-$8M
—
$16M
Mar '24
$0
-$12M
—
—
-21.6%
-11.9%
-$12M
—
$24M
Dec '23
$0
-$19M
—
—
-28.0%
-15.7%
-$7M
—
$36M
Sep '23
$255000
-$15M
0.0%
-17206.3%
-18.0%
-11.3%
-$17M
—
$39M
Jun '23
$687000
-$19M
0.0%
-2210.8%
-19.2%
-13.0%
-$17M
—
$37M
Mar '23
$1M
-$19M
0.0%
-1444.4%
-16.7%
-11.6%
-$23M
—
$32M
Dec '22
-$191000
-$58M
0.0%
8792.7%
-45.7%
-32.2%
-$18M
—
$58M
Sep '22
$2M
-$17M
0.0%
-972.8%
-11.9%
-8.8%
-$24M
—
$115M
Jun '22
$1M
-$12M
0.0%
-1964.9%
-7.5%
-5.7%
-$17M
—
$140M
Mar '22
$854000
-$12M
0.0%
-1376.8%
9.7%
-5.1%
-$17M
—
$38M
Dec '21
$543000
-$3M
0.0%
-619.3%
3.0%
-3.5%
-$16M
—
$56M
Sep '21
$926000
-$291680
0.0%
-31.8%
0.3%
-0.1%
-$10M
—
$74M
Valuation over time
How the market has priced SNTI against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has risen from 11.0× (Mar '23) to 495.5× (Sep '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is SNTI growing its revenue and profit?
Over the past 4 years, Senti Biosciences Holdings, Inc.'s revenue has declined 68.7% per year. These are computed facts, not advice.
How much debt does SNTI have?
As of FY2025, Senti Biosciences Holdings, Inc. reported — of total debt against $16M of cash.
What is SNTI's profit margin?
In FY2025, gross margin was —, operating margin -312631.8%, and net margin -279263.6%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.