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SNDX Financials Syndax Pharmaceuticals Inc

12 years of revenue, profit, cash flow and balance-sheet history through FY2025, from SEC filings — with a computed, factual read of the trend. Updated Overview →

Growth & profitability

  • Revenue has grown 157.7% per year over the past 5 years.
  • Operating margin has expanded, at -158.4% in the latest year.

Financial health

  • Operating income covered interest expense -45514.0× in the latest year.
  • The company is unprofitable and has less than a year of cash runway at its current free-cash-flow burn.
Revenue & net income
-$319M -$73M $172M $0 2014 2016 2018 2020 2022 2024
RevenueNet income
Margins (gross / operating / net)
-5002% -2491% 19% 0% 2014 2016 2018 2020 2022 2024
GrossOperatingNet
Return on equity & assets (ROE / ROA)
-442% -214% 13% 0% 2014 2016 2018 2020 2022 2024
ROEROA
Free cash flow (CFO − capex)
-$323M -$147M $29M $0 2014 2016 2018 2020 2022 2024
Free cash flow
Cash vs total debt
$0 $148M $295M 2014 2016 2018 2020 2022 2024
CashTotal debt
Cash flow: operating / investing / financing
-$323M $15M $353M $0 2014 2016 2018 2020 2022 2024
OperatingInvestingFinancing

Key annual figures

FYRevenueNet incomeGross MOp MROEROAFCFTotal debtCash
2025 $172M -$285M 0.0% -158.4% -441.6% -53.9% -$323M $135M
2024 $24M -$319M 0.0% -1434.4% -110.6% -44.0% -$275M $154M
2023 $0 -$209M -37.8% -34.2% -$161M $295M
2022 $0 -$149M -31.9% -30.0% -$134M $74M
2021 $140M $25M 0.0% 18.8% 6.1% 5.5% $29M $222M
2020 $2M -$73M 0.0% -4708.2% -29.0% -24.3% -$71M $115M
2019 $2M -$56M 0.0% -3792.9% -177.4% -88.2% $25M
2018 $2M -$74M 0.0% -5001.7% -139.4% -88.1% -$69M $34M
2017 $2M -$61M 0.0% -2939.0% -58.3% -44.3% -$47M $35M
2016 $1M -$44M 0.0% -3587.4% -52.9% -40.8% -$35M $24M
2015 -$24M 9.6% -26.8% $23M
2014 -$20M 13.0% $10M

Valuation over time

How the market has priced SNDX against its own fundamentals since 2023-03 — each month-end's share price set against the most recent annual filing, so the multiple moves as price runs ahead of (or behind) earnings. Split-adjusted.

Price / sales (P/S)
0.0 37.4 74.8 Mar '23 Sep '23 Mar '24 Sep '24 Mar '25 Sep '25 Mar '26 Sep '26
P/S

Frequently asked questions

Is SNDX growing its revenue and profit?

Over the past 5 years, Syndax Pharmaceuticals Inc's revenue has grown 157.7% per year. These are computed facts, not advice.

How much debt does SNDX have?

As of FY2025, Syndax Pharmaceuticals Inc reported — of total debt against $135M of cash; operating income covered interest expense -45514.0×.

What is SNDX's profit margin?

In FY2025, gross margin was —, operating margin -158.4%, and net margin -165.6%.

Where does this data come from?

All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.

Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted · growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price against the latest annual filing. Informational only — not investment advice.