15 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has grown 15.7% per year over the past 5 years.
Operating margin has expanded, at -98.2% in the latest year.
Financial health
Total debt ($54M) exceeds cash ($34M); net debt is $20M.
Total debt has grown faster than revenue (35.9% vs 15.7% per year).
The company is unprofitable and has less than a year of cash runway at its current free-cash-flow burn.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
2025
$50M
-$50M
99.4%
-98.2%
-$68M
$54M
$34M
2024
$31M
-$200M
98.0%
-634.2%
-$180M
$100M
$67M
2023
$1M
-$177M
92.9%
-14265.0%
-$162M
$100M
$22M
2022
$139000
-$102M
100.0%
-72489.2%
-$90M
$49M
$46M
2021
$298000
-$88M
100.0%
-29224.8%
-$88M
$0
$64M
2020
$24M
-$59M
92.0%
-199.2%
-$143M
$12M
$126M
2019
$322M
$130M
99.0%
43.9%
$114M
$249M
$36M
2018
$63M
-$121M
96.1%
-163.4%
-$149M
$250M
$80M
2017
$92M
-$123M
97.9%
-142.5%
-$186M
$252M
$62M
2016
$79M
-$131M
100.0%
-160.5%
-$176M
$101M
$47M
2015
$130M
-$5M
0.0%
1.1%
$184M
$106M
$203M
2014
$23M
-$100M
0.0%
-439.2%
-$76M
$108M
$137M
2013
$2M
-$104M
0.0%
-4607.2%
-$93M
$22M
$37M
2012
$1M
-$110M
0.0%
-9955.5%
-$95M
$23M
$30M
2011
$2M
-$116M
0.0%
-6170.6%
-$89M
$25M
$186M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
Mar '26
$21M
-$1M
99.5%
-4.7%
—
$50M
$38M
Dec '25
$5M
-$16M
96.3%
-269.1%
-$17M
$54M
$34M
Sep '25
$14M
-$13M
99.9%
-85.9%
-$24M
$57M
$50M
Jun '25
$29M
$3M
99.9%
12.9%
—
$56M
$21M
Mar '25
$1M
-$25M
97.6%
-2034.8%
—
$101M
$63M
Dec '24
$27M
-$34M
98.7%
-123.3%
-$22M
$100M
$67M
Sep '24
$2M
-$65M
95.9%
-3639.6%
-$54M
$100M
$35M
Jun '24
$2M
-$53M
89.9%
-3360.9%
-$49M
$99M
$36M
Mar '24
$1M
-$48M
97.3%
-4011.8%
-$55M
$100M
$96M
Dec '23
$702000
-$50M
90.0%
-6657.7%
-$51M
$100M
$22M
Sep '23
$162000
-$51M
95.7%
-30636.4%
-$42M
$99M
$21M
Jun '23
$317000
-$45M
97.5%
-13955.8%
-$38M
$99M
$102M
Mar '23
$24000
-$32M
100.0%
-129758.3%
-$32M
$49M
$26M
Dec '22
$28000
-$30M
100.0%
-108135.7%
-$23M
$49M
$46M
Sep '22
$39000
-$23M
100.0%
-59217.9%
-$19M
$24M
$19M
Jun '22
$35000
-$25M
100.0%
-68591.4%
-$24M
$24M
$21M
Mar '22
—
-$23M
—
—
-$23M
$24M
$60M
Sep '21
$23000
-$23M
100.0%
-99834.8%
-$17M
—
$92M
Jun '21
$234000
-$18M
100.0%
-7674.8%
-$23M
—
$90M
Mar '21
$27000
-$21M
100.0%
-77181.5%
-$25M
—
$98M
Valuation over time
How the market has priced LXRX against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has fallen from 7733.5× (Mar '23) to 20.5× (Jun '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is LXRX growing its revenue and profit?
Over the past 5 years, Lexicon Pharmaceuticals, Inc.'s revenue has grown 15.7% per year. These are computed facts, not advice.
How much debt does LXRX have?
As of FY2025, Lexicon Pharmaceuticals, Inc. reported $54M of total debt against $34M of cash.
What is LXRX's profit margin?
In FY2025, gross margin was 99.4%, operating margin -98.2%, and net margin -101.1%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.