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KRYS Financials Krystal Biotech, Inc.

10 years of revenue, profit, cash flow and balance-sheet history through FY2025, from SEC filings — with a computed, factual read of the trend. Updated Overview →

Revenue & net income
-$140M $125M $389M $0 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025
RevenueNet income
Margins (gross / operating / net)
-216% -82% 53% 0% 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025
GrossOperatingNet
Free cash flow (CFO − capex)
-$154M $18M $189M $0 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025
Free cash flow
Cash vs total debt
$0 $248M $496M 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025
CashTotal debt
Cash flow: operating / investing / financing
-$227M $60M $348M $0 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025
OperatingInvestingFinancing

Key annual figures

FYRevenueNet incomeGross MOp MFCFTotal debtCash
2025 $389M $205M 0.0% 41.5% $189M $496M
2024 $291M $89M 0.0% 22.6% $119M $345M
2023 $51M $11M 0.0% -216.2% -$101M $358M
2022 $0 -$140M -$154M $162M
2021 $0 -$70M -$116M $341M
2020 -$32M -$41M $268M
2019 -$19M -$25M $188M
2018 -$11M -$12M $104M
2017 -$8M $50M
2016 -$1M $2M

Valuation over time

How the market has priced KRYS against its own fundamentals since 2023-03 — each month-end's share price set against the most recent annual filing, so the multiple moves as price runs ahead of (or behind) earnings. Split-adjusted.

Price / earnings (P/E)
0.0 281.6 563.1 Mar '23 Aug '23 Jan '24 Jun '24 Nov '24 Apr '25 Sep '25 Feb '26
P/E
Price / sales (P/S)
0.0 60.7 121.4 Mar '23 Aug '23 Jan '24 Jun '24 Nov '24 Apr '25 Sep '25 Feb '26
P/S

Frequently asked questions

Is KRYS growing its revenue and profit?

See the revenue and net-income charts above for Krystal Biotech, Inc.'s multi-year trend.

How much debt does KRYS have?

As of FY2025, Krystal Biotech, Inc. reported — of total debt against $496M of cash.

What is KRYS's profit margin?

In FY2025, gross margin was —, operating margin 41.5%, and net margin 52.6%.

What is KRYS's P/E ratio?

As of Jun '26, Krystal Biotech, Inc. traded at a price-to-earnings ratio of about 51.8× (market cap ÷ latest annual net income). The valuation charts above show how its P/E, P/S have moved with the share price. These are computed facts, not advice.

Where does this data come from?

All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.

Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted · growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price against the latest annual filing. Informational only — not investment advice.