KPTI Karyopharm Therapeutics Inc.

$1.76 -1.40%

Updated 16 d ago

Healthcare · Pharmaceutical Preparations

Karyopharm Therapeutics Inc. (KPTI) is a healthcare company in the Pharmaceutical Preparations industry, with a market capitalization of $40 million. Shares last traded at $1.76, 84.0% below their 52-week high. Over the past year the stock is down 75.1%. Net profit margin is -153.3%, below the peer median of -8.9%. Revenue grew 0.6% year over year.

Market Cap

$40M

Shares Out

22.7M

EPS (TTM)

$-22.79

P/E Ratio

—

P/S Ratio

0.27

P/B Ratio

—

Dividend / Share

—

Dividend Yield

—

52-Week High

$10.97

52-Week Low

$1.72

Volume

34,135

Avg Vol (3m)

56,169.714

Performance

-9.74%

-8.81%

-80.66%

-79.94%

YTD

-75.72%

-75.11%

Chart

Full chart →

Daily candles · volume · SMA(20)/SMA(50) · Databento EQUS.MINI.

Technicals

RSI (14)

26.87

SMA (50)

$5.33

SMA (200)

$7.14

Price vs SMA50

-67.01%

Price vs SMA200

-75.33%

ATR (14)

$0.31

Full technical analysis (26 indicators, D/W/M) →

Financials

Revenue

$147M

Net Income

$-225M

Gross Margin

—

Operating Margin

-56.2%

Net Margin

-153.3%

Return on Equity

68.1%

Return on Assets

-201.9%

Current Ratio

0.79

Debt / Equity

-0.51

Revenue Growth (YoY)

+0.6%

Latest reported annual period ending 2026-06-30 · SEC EDGAR/XBRL.

Full financials — revenue, cash flow & debt over time →

Recent earnings

Period	EPS (diluted)	Reported
Q2 2026	$-3.51	2026-08-13
Q1 2026	$-1.24	2026-05-14
FY 2025	$-17.93	2026-02-13
Q3 2025	$-10.93	2025-11-03
Q2 2026	$-7.11	2026-08-13
Q1 2026	$-2.77	2026-05-14

Full earnings history →

Pharmaceutical Preparations peers

KPTI vs 14 industry peers (Pharmaceutical Preparations), by market cap. Updated 16 d ago

P/S vs peers

0.27 / 11.11 med

-98% discount

Net margin vs peers

-153.3% / -8.9% med

below median

1–14 of 14


LLY	Lilly (Eli)	$1.09T	40.86	13.70	33.5%	-0.02%
JNJ	Johnson & Johnson	$670.6B	31.88	6.85	21.5%	+1.04%
ONC	Beone Medicines Ltd.	$535.9B	817.25	87.43	10.7%	+0.23%
ABBV	AbbVie	$459.8B	72.87	7.14	9.8%	-0.57%
MRK	Merck	$375.8B	118.44	5.65	4.8%	+0.44%
ABT	Abbott Laboratories	$189.5B	30.20	4.20	13.9%	-1.50%
PFE	Pfizer	$164.2B	37.91	2.58	6.8%	-0.76%
VRTX	Vertex Pharmaceuticals	$141.5B	32.11	11.24	35.0%	+0.24%
BMY	Bristol Myers Squibb	$139.1B	14.98	2.83	18.9%	+0.62%
REGN	Regeneron Pharmaceuticals	$87.2B	20.15	5.61	27.9%	-1.02%
TEVA	Teva Pharmaceutical Industries Ltd	$42.6B	60.41	2.46	4.1%	-2.32%
ALNY	Alnylam Pharmaceuticals	$35.4B	43.77	9.52	21.8%	-1.10%
ZTS	Zoetis	$31.5B	12.05	3.31	27.5%	+0.16%
RPRX	Royalty Pharma Plc	$28.2B	34.56	11.11	32.1%	+1.24%

Source: SEC EDGAR (fundamentals/EPS/dividends) · Databento EQUS.MINI (prices) · market cap & yield computed by tradmap. Informational only — not financial advice.