IONS Ionis Pharmaceuticals Inc

$58.13 -5.21%

Updated 16 d ago

Healthcare · Pharmaceutical Preparations

Ionis Pharmaceuticals Inc (IONS) is a healthcare company in the Pharmaceutical Preparations industry, with a market capitalization of $9.7 billion. Shares last traded at $58.13, 33.6% below their 52-week high. Over the past year the stock is down 3.9%. Net profit margin is -64.7%, below the peer median of -8.9%. Revenue grew 33.8% year over year.

Market Cap

$9.7B

Shares Out

166.2M

EPS (TTM)

$-2.91

P/E Ratio

—

P/S Ratio

11.05

P/B Ratio

21.97

Dividend / Share

—

Dividend Yield

—

52-Week High

$87.49

52-Week Low

$48.00

Volume

254,040

Avg Vol (3m)

172,143.111

Performance

-6.92%

+7.28%

-22.62%

-22.64%

YTD

-26.99%

-3.91%

Chart

Full chart →

Daily candles · volume · SMA(20)/SMA(50) · Databento EQUS.MINI.

Technicals

RSI (14)

45.00

SMA (50)

$61.64

SMA (200)

$73.49

Price vs SMA50

-5.70%

Price vs SMA200

-20.91%

ATR (14)

$2.17

Full technical analysis (26 indicators, D/W/M) →

Financials

Revenue

$874M

Net Income

$-565M

Gross Margin

98.2%

Operating Margin

-68.0%

Net Margin

-64.7%

Return on Equity

-128.5%

Return on Assets

-18.9%

Current Ratio

7.89

Debt / Equity

4.12

Revenue Growth (YoY)

+33.8%

Latest reported annual period ending 2026-06-30 · SEC EDGAR/XBRL.

Full financials — revenue, cash flow & debt over time →

Recent earnings

Period	EPS (diluted)	Reported
Q2 2026	$-1.25	2026-07-29
Q1 2026	$-0.56	2026-04-29
FY 2025	$-2.38	2026-02-26
Q3 2025	$-0.95	2025-10-29
Q2 2026	$-0.15	2026-07-29
Q1 2026	$-0.93	2026-04-29

Full earnings history →

Pharmaceutical Preparations peers

IONS vs 14 industry peers (Pharmaceutical Preparations), by market cap. Updated 16 d ago

P/S vs peers

11.05 / 11.11 med

-1% discount

Net margin vs peers

-64.7% / -8.9% med

below median

1–14 of 14


LLY	Lilly (Eli)	$1.09T	40.86	13.70	33.5%	-0.02%
JNJ	Johnson & Johnson	$670.6B	31.88	6.85	21.5%	+1.04%
ONC	Beone Medicines Ltd.	$535.9B	817.25	87.43	10.7%	+0.23%
ABBV	AbbVie	$459.8B	72.87	7.14	9.8%	-0.57%
MRK	Merck	$375.8B	118.44	5.65	4.8%	+0.44%
ABT	Abbott Laboratories	$189.5B	30.20	4.20	13.9%	-1.50%
PFE	Pfizer	$164.2B	37.91	2.58	6.8%	-0.76%
VRTX	Vertex Pharmaceuticals	$141.5B	32.11	11.24	35.0%	+0.24%
BMY	Bristol Myers Squibb	$139.1B	14.98	2.83	18.9%	+0.62%
REGN	Regeneron Pharmaceuticals	$87.2B	20.15	5.61	27.9%	-1.02%
TEVA	Teva Pharmaceutical Industries Ltd	$42.6B	60.41	2.46	4.1%	-2.32%
ALNY	Alnylam Pharmaceuticals	$35.4B	43.77	9.52	21.8%	-1.10%
ZTS	Zoetis	$31.5B	12.05	3.31	27.5%	+0.16%
RPRX	Royalty Pharma Plc	$28.2B	34.56	11.11	32.1%	+1.24%

Source: SEC EDGAR (fundamentals/EPS/dividends) · Databento EQUS.MINI (prices) · market cap & yield computed by tradmap. Informational only — not financial advice.