13 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has declined 55.1% per year over the past 5 years.
Operating margin has contracted, at -40856.3% in the latest year.
Financial health
Total debt has grown faster than revenue (46.1% vs -55.1% per year).
The company is unprofitable and has less than a year of cash runway at its current free-cash-flow burn.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
2025
$190000
-$74M
0.0%
-40856.3%
-109.8%
-79.7%
-$62M
—
$11M
2024
$235000
-$64M
0.0%
-28899.6%
-91.4%
-66.1%
-$69M
—
$11M
2023
$353000
-$50M
0.0%
-15557.8%
-55.6%
-41.8%
-$37M
—
$23M
2022
$10M
-$45M
0.0%
-446.8%
-63.4%
-47.3%
-$44M
—
$10M
2021
$0
-$34M
—
—
-30.9%
-29.2%
-$33M
—
$2M
2020
$10M
-$16M
0.0%
-152.2%
-51.3%
-41.9%
-$16M
—
$17M
2019
$422000
-$16M
0.0%
-5445.0%
-76.6%
-44.8%
-$20M
—
$9M
2018
—
-$35M
—
—
-102.6%
-65.4%
-$32M
$16M
$23M
2017
—
-$48M
—
—
-75.0%
-53.9%
-$44M
$20M
$21M
2016
—
-$58M
—
—
-92.1%
-71.8%
-$53M
$10M
$38M
2015
—
-$48M
—
—
-41.7%
-37.0%
—
$5M
$53M
2014
—
-$24M
—
—
26.8%
-118.0%
—
—
$14M
2013
—
-$20M
—
—
30.3%
—
—
—
$36M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
Jun '26
—
-$10M
—
—
-21.1%
-14.8%
-$9M
—
$16M
Mar '26
—
-$11M
—
—
-18.6%
-13.5%
-$13M
—
$10M
Dec '25
$0
-$14M
—
—
-20.7%
-15.0%
-$12M
—
$11M
Sep '25
$190000
-$26M
0.0%
-14076.3%
-32.1%
-24.1%
-$21M
—
$6M
Jun '25
$0
-$20M
—
—
-26.1%
-19.2%
-$14M
—
$17M
Mar '25
$0
-$15M
—
—
-19.8%
-15.3%
-$15M
—
$10M
Dec '24
$0
-$15M
—
—
-21.4%
-15.5%
-$13M
—
$11M
Sep '24
$0
-$17M
—
—
-26.4%
-18.8%
-$13M
—
$11M
Jun '24
$0
-$16M
—
—
-20.0%
-15.4%
-$20M
—
$7M
Mar '24
$235000
-$15M
0.0%
-7079.1%
-18.3%
-13.7%
-$22M
—
$7M
Dec '23
$0
-$15M
—
—
-16.3%
-12.2%
-$11M
—
$23M
Sep '23
$353000
-$11M
0.0%
-3573.7%
-11.5%
-9.1%
-$10M
—
$10M
Jun '23
$0
-$12M
—
—
-11.6%
-9.3%
-$14M
—
$12M
Mar '23
$0
-$12M
—
—
-10.9%
-8.7%
-$2M
—
$21M
Dec '22
$10M
-$8M
0.0%
-76.5%
-10.5%
-7.9%
-$11M
—
$10M
Sep '22
$0
-$13M
—
—
-17.2%
-13.8%
-$13M
—
$18M
Jun '22
—
-$12M
—
—
-14.3%
-12.9%
-$9M
—
$8M
Mar '22
—
-$12M
—
—
-12.3%
-11.6%
-$10M
—
$8M
Dec '21
—
-$9M
—
—
-7.8%
-7.4%
-$8M
—
$2M
Sep '21
—
-$8M
—
—
-6.5%
-6.2%
-$12M
—
$60M
Valuation over time
How the market has priced ATYR against its own fundamentals since 2024-06 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has fallen from 430.7× (Jun '24) to 258.6× (Sep '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is ATYR growing its revenue and profit?
Over the past 5 years, aTYR PHARMA INC's revenue has declined 55.1% per year. These are computed facts, not advice.
How much debt does ATYR have?
As of FY2025, aTYR PHARMA INC reported — of total debt against $11M of cash.
What is ATYR's profit margin?
In FY2025, gross margin was —, operating margin -40856.3%, and net margin -39009.5%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.