14 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has declined 25.3% per year over the past 5 years.
Operating margin has contracted, at -4974.3% in the latest year.
Financial health
Total debt has grown faster than revenue (51.1% vs -25.3% per year).
The company is unprofitable and has less than a year of cash runway at its current free-cash-flow burn.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
2025
$8M
-$346M
0.0%
-4974.3%
-59.5%
-54.6%
-$280M
—
$199M
2024
$0
-$234M
—
—
-31.0%
-29.4%
-$184M
—
$143M
2023
$0
-$182M
—
—
-19.7%
-18.9%
-$157M
—
$149M
2022
$9M
-$125M
0.0%
-1368.9%
-17.4%
-16.6%
-$104M
—
$57M
2021
$18M
-$79M
0.0%
-428.4%
-14.3%
-13.8%
-$72M
—
$176M
2020
$32M
-$29M
0.0%
-97.3%
-16.8%
-15.2%
-$51M
—
$45M
2019
$7M
-$42M
0.0%
-627.0%
-45.2%
-28.2%
-$6M
$16M
$25M
2018
—
-$34M
—
—
-33.4%
-28.2%
-$35M
$15M
$68M
2017
—
-$31M
—
—
-85.4%
-66.6%
-$29M
$7M
$20M
2016
—
-$23M
—
—
-36.0%
-34.1%
—
—
$17M
2015
—
-$16M
—
—
-25.8%
-24.6%
—
—
$59M
2014
—
$13M
—
—
17.9%
14.9%
—
—
$72M
2013
—
$12M
—
—
-15.4%
22.1%
—
—
$38M
2012
—
-$4M
—
—
4.8%
—
—
—
$60M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
Jun '26
$0
-$111M
—
—
-8.9%
-8.5%
-$96M
—
$120M
Mar '26
$0
-$102M
—
—
-7.6%
-7.4%
-$89M
—
$546M
Dec '25
$0
-$105M
—
—
-18.1%
-16.6%
-$82M
—
$199M
Sep '25
$0
-$91M
—
—
-16.2%
-15.0%
-$72M
—
$105M
Jun '25
$0
-$85M
—
—
-13.4%
-12.6%
-$64M
—
$135M
Mar '25
$8M
-$65M
0.0%
-969.8%
-9.2%
-8.8%
-$62M
—
$117M
Dec '24
$0
-$66M
—
—
-8.7%
-8.2%
-$55M
—
$143M
Sep '24
$0
-$63M
—
—
-7.9%
-7.5%
-$50M
—
$88M
Jun '24
$0
-$58M
—
—
-6.9%
-6.6%
-$33M
—
$137M
Mar '24
$0
-$48M
—
—
-5.4%
-5.2%
-$46M
—
$59M
Dec '23
—
-$45M
—
—
-4.8%
-4.6%
-$35M
—
$149M
Sep '23
—
-$48M
—
—
-7.6%
-7.2%
-$49M
—
$100M
Jun '23
—
-$47M
—
—
-7.3%
-6.9%
-$35M
—
$65M
Mar '23
—
-$42M
—
—
-6.1%
-5.8%
-$37M
—
$70M
Dec '22
$0
-$37M
—
—
-5.2%
-5.0%
-$34M
—
$57M
Sep '22
$132000
-$37M
0.0%
-28884.8%
-4.9%
-4.8%
-$31M
—
$103M
Jun '22
$536000
-$31M
0.0%
-5655.8%
-4.0%
-3.9%
-$17M
—
$370M
Mar '22
$9M
-$20M
0.0%
-198.1%
-3.6%
-3.5%
-$19M
—
$117M
Dec '21
$4M
-$26M
0.0%
-664.7%
-4.6%
-4.5%
-$21M
—
$176M
Sep '21
$8M
-$15M
0.0%
-192.0%
-6.2%
-5.8%
-$15M
—
$88M
Valuation over time
How the market has priced XENE against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has risen from 367.5× (Mar '23) to 779.9× (Sep '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is XENE growing its revenue and profit?
Over the past 5 years, Xenon Pharmaceuticals Inc.'s revenue has declined 25.3% per year. These are computed facts, not advice.
How much debt does XENE have?
As of FY2025, Xenon Pharmaceuticals Inc. reported — of total debt against $199M of cash.
What is XENE's profit margin?
In FY2025, gross margin was —, operating margin -4974.3%, and net margin -4612.1%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.