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VYNE Financials VYNE Therapeutics Inc.

11 years of revenue, profit, cash flow and balance-sheet history through FY2025, from SEC filings — with a computed, factual read of the trend. Updated Overview →

Growth & profitability

  • Revenue has declined 51.4% per year over the past 5 years.
  • Operating margin has contracted, at -5219.1% in the latest year.

Financial health

  • The company holds more cash ($24M) than total debt ($0).
  • The company is unprofitable and has less than a year of cash runway at its current free-cash-flow burn.
Revenue & net income
-$256M -$117M $21M $0 2015 2017 2019 2021 2023 2025
RevenueNet income
Margins (gross / operating / net)
-21642% -10771% 100% 0% 2015 2017 2019 2021 2023 2025
GrossOperatingNet
Free cash flow (CFO − capex)
-$34M -$17M $0 2015 2017 2019 2021 2023 2025
Free cash flow
Cash vs total debt
$0 $29M $58M 2015 2017 2019 2021 2023 2025
CashTotal debt
Cash flow: operating / investing / financing
-$137M -$22M $92M $0 2015 2017 2019 2021 2023 2025
OperatingInvestingFinancing

Key annual figures

FYRevenueNet incomeGross MOp MFCFTotal debtCash
2025 $570000 -$26M 0.0% -5219.1% -$33M $0 $24M
2024 $501000 -$40M 0.0% -8710.0% -$34M $0 $20M
2023 $424000 -$28M 0.0% -6900.5% -$25M $0 $31M
2022 $477000 -$23M 0.0% -7189.7% $0 $31M
2021 $931000 -$73M -259.6% -4179.5% $0 $42M
2020 $21M -$256M 93.4% -1203.0% $33M $58M
2019 $443000 -$95M 100.0% -21641.8% $33M $44M
2018 $4M -$74M 100.0% -2083.2% $28M
2017 -$29M $10M
2016 -$14M $4M
2015 -$5M $44M

Valuation over time

How the market has priced VYNE against its own fundamentals since 2023-03 — each month-end's share price set against the most recent annual filing, so the multiple moves as price runs ahead of (or behind) earnings. Split-adjusted.

Price / sales (P/S)
0.0 219.9 439.8 Mar '23 Aug '23 Jan '24 Jun '24 Nov '24 Apr '25 Sep '25 Feb '26
P/S

Frequently asked questions

Is VYNE growing its revenue and profit?

Over the past 5 years, VYNE Therapeutics Inc.'s revenue has declined 51.4% per year. These are computed facts, not advice.

How much debt does VYNE have?

As of FY2025, VYNE Therapeutics Inc. reported $0 of total debt against $24M of cash.

What is VYNE's profit margin?

In FY2025, gross margin was —, operating margin -5219.1%, and net margin -4646.1%.

Where does this data come from?

All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.

Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted · growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price against the latest annual filing. Informational only — not investment advice.