15 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has grown 14.1% per year over the past 5 years.
Net income has grown slower than revenue (7.8% vs 14.1% per year).
Operating margin has contracted, at 34.8% in the latest year.
Free cash flow has grown 1.3% per year over the past 5 years.
Financial health
Operating income covered interest expense 314× in the latest year.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
2025
$12.0B
$4.0B
86.2%
34.8%
21.2%
15.4%
$3.2B
—
$5.1B
2024
$11.0B
-$536M
86.1%
-2.1%
-3.3%
-2.4%
-$790M
—
$4.6B
2023
$9.9B
$3.6B
87.2%
38.8%
20.6%
15.9%
$3.3B
—
$10.4B
2022
$8.9B
$3.3B
87.9%
48.2%
23.9%
18.3%
$3.9B
—
$10.5B
2021
$7.6B
$2.3B
88.1%
36.7%
23.2%
17.4%
$2.4B
—
$6.8B
2020
$6.2B
$2.7B
88.1%
46.0%
31.2%
23.1%
$3.0B
—
$6.0B
2019
$4.2B
$1.2B
86.8%
28.8%
19.3%
14.1%
$1.5B
—
$3.1B
2018
$3.0B
$2.1B
86.6%
20.8%
47.3%
33.6%
$1.2B
—
$2.7B
2017
$2.5B
$263M
88.9%
5.0%
13.0%
7.4%
$746M
—
$1.7B
2016
$1.7B
-$112M
87.6%
0.6%
-9.7%
-3.9%
$180M
—
$1.2B
2015
—
-$556M
—
—
-59.2%
-22.3%
-$411M
—
$715M
2014
—
-$739M
—
—
-68.7%
-31.6%
-$624M
—
$625M
2013
—
-$445M
—
—
-32.8%
-19.2%
-$112M
—
$569M
2012
—
-$107M
—
—
-10.7%
-3.9%
$197M
—
$489M
2011
—
$30M
—
—
3.8%
1.3%
$109M
—
$475M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
Jun '26
$3.3B
$1.1B
85.3%
37.4%
5.4%
4.0%
$1.0B
—
$6.1B
Mar '26
$3.0B
$1.0B
86.8%
38.1%
5.3%
3.9%
$1.3B
—
$5.5B
Dec '25
$3.2B
$1.2B
85.4%
37.8%
6.4%
4.6%
$349M
—
$5.1B
Sep '25
$3.1B
$1.1B
86.5%
38.6%
6.3%
4.4%
$1.1B
—
$4.9B
Jun '25
$3.0B
$1.0B
86.3%
38.8%
6.0%
4.3%
$927M
—
$5.0B
Mar '25
$2.8B
$646M
86.9%
22.7%
3.9%
2.8%
$778M
—
$4.7B
Dec '24
$2.9B
$913M
85.5%
35.2%
5.6%
4.1%
$492M
—
$4.6B
Sep '24
$2.8B
$1.0B
85.8%
40.3%
6.7%
4.7%
$1.3B
—
$5.2B
Jun '24
$2.6B
-$3.6B
85.9%
-132.9%
-24.3%
-17.9%
-$3.8B
—
$4.6B
Mar '24
$2.7B
$1.1B
87.3%
42.4%
5.9%
4.6%
$1.2B
—
$9.2B
Dec '23
$2.5B
$969M
85.4%
39.3%
5.5%
4.3%
$177M
—
$10.4B
Sep '23
$2.5B
$1.0B
87.2%
41.8%
6.3%
4.8%
$1.2B
—
$11.1B
Jun '23
$2.5B
$916M
87.6%
41.2%
5.9%
4.5%
$1.1B
—
$10.2B
Mar '23
$2.4B
$700M
88.8%
32.8%
4.8%
3.7%
$858M
—
$9.3B
Dec '22
$2.3B
$819M
87.7%
44.9%
5.9%
4.5%
$1.0B
—
$10.5B
Sep '22
$2.3B
$931M
87.6%
48.3%
7.1%
5.6%
$901M
—
$9.2B
Jun '22
$2.2B
$811M
88.1%
50.4%
6.8%
5.2%
$1.1B
—
$8.7B
Mar '22
$2.1B
$762M
88.3%
49.6%
7.0%
5.3%
$893M
—
$7.6B
Dec '21
$2.1B
$770M
88.1%
42.3%
7.6%
5.7%
$933M
—
$6.8B
Sep '21
$2.0B
$852M
88.1%
53.1%
8.9%
6.8%
$875M
—
$6.3B
Valuation over time
How the market has priced VRTX against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-earnings ratio has risen from 24.0× (Mar '23) to 35.8× (Sep '26).
The price-to-sales ratio has risen from 8.9× (Mar '23) to 11.8× (Sep '26).
Price / earnings (P/E)
P/E
Price / sales (P/S)
P/S
Frequently asked questions
Is VRTX growing its revenue and profit?
Over the past 5 years, Vertex Pharmaceuticals's revenue has grown 14.1% per year, and net income grown 7.8% per year. These are computed facts, not advice.
How much debt does VRTX have?
As of FY2025, Vertex Pharmaceuticals reported — of total debt against $5.1B of cash; operating income covered interest expense 314×.
What is VRTX's profit margin?
In FY2025, gross margin was 86.2%, operating margin 34.8%, and net margin 32.9%.
What is VRTX's P/E ratio?
As of Sep '26, Vertex Pharmaceuticals traded at a price-to-earnings ratio of about 35.8× (market cap ÷ latest annual net income). The valuation charts above show how its P/E, P/S have moved with the share price. These are computed facts, not advice.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.