9 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has grown 33.1% per year over the past 5 years.
Operating margin has expanded, at -36.2% in the latest year.
Financial health
Total debt has grown slower than revenue (-34.5% vs 33.1% per year).
The company is unprofitable; at its current free-cash-flow burn it has roughly 2.4 years of cash runway.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
2025
$377M
-$78M
50.7%
-36.2%
-$76M
—
$183M
2024
$313M
-$209M
42.6%
-70.6%
-$69M
—
$226M
2023
$245M
-$205M
36.6%
-88.6%
-$170M
—
$286M
2022
$204M
-$218M
41.4%
-115.3%
-$226M
—
$379M
2021
$132M
-$152M
39.1%
-115.4%
-$139M
—
$466M
2020
$90M
-$140M
31.8%
-155.5%
-$152M
$4M
$94M
2019
$54M
-$108M
12.8%
-200.1%
-$103M
$8M
$47M
2018
$25M
-$71M
-26.6%
-277.5%
-$70M
$10M
$81M
2017
$11M
-$59M
-123.1%
-543.2%
-$58M
—
$31M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
Mar '26
$111M
-$44M
51.6%
-41.4%
-$25M
—
$123M
Dec '25
$104M
-$31M
52.0%
-31.7%
-$35M
—
$149M
Sep '25
$99M
-$27M
51.3%
-30.2%
-$24M
—
$183M
Jun '25
$96M
$20M
53.4%
-31.4%
-$11M
—
$201M
Mar '25
$93M
-$39M
49.6%
-44.8%
-$17M
—
$210M
Dec '24
$89M
-$32M
48.3%
-39.1%
-$24M
—
$221M
Sep '24
$85M
-$35M
45.1%
-42.5%
-$17M
—
$226M
Jun '24
$81M
-$86M
43.3%
-109.2%
-$7M
—
$239M
Mar '24
$75M
-$45M
41.0%
-64.9%
-$20M
—
$243M
Dec '23
$71M
-$43M
40.5%
-65.7%
-$24M
—
$266M
Sep '23
$67M
-$46M
36.6%
-74.9%
-$23M
—
$286M
Jun '23
$64M
-$57M
34.4%
-95.4%
-$28M
—
$307M
Mar '23
$60M
-$59M
30.8%
-102.4%
-$53M
—
$315M
Dec '22
$54M
-$42M
45.7%
-82.3%
-$66M
—
$317M
Sep '22
$57M
-$51M
44.9%
-99.2%
-$18M
—
$379M
Jun '22
$56M
-$61M
44.8%
-109.0%
-$75M
—
$376M
Mar '22
$48M
-$61M
38.3%
-126.3%
-$74M
—
$408M
Dec '21
$42M
-$46M
35.6%
-133.1%
-$59M
—
$192M
Sep '21
$38M
-$41M
40.7%
-104.9%
-$43M
—
$466M
Jun '21
$35M
-$40M
40.2%
-120.3%
-$35M
—
$475M
Valuation over time
How the market has priced TWST against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has risen from 4.6× (Mar '23) to 16.0× (Jun '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is TWST growing its revenue and profit?
Over the past 5 years, Twist Bioscience Corp's revenue has grown 33.1% per year. These are computed facts, not advice.
How much debt does TWST have?
As of FY2025, Twist Bioscience Corp reported — of total debt against $183M of cash.
What is TWST's profit margin?
In FY2025, gross margin was 50.7%, operating margin -36.2%, and net margin -20.6%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.