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TWST Financials Twist Bioscience Corp

9 years of revenue, profit, cash flow and balance-sheet history through FY2025, from SEC filings — with a computed, factual read of the trend. Updated Overview →

Growth & profitability

  • Revenue has grown 33.1% per year over the past 5 years.
  • Operating margin has expanded, at -36.2% in the latest year.

Financial health

  • Total debt has grown slower than revenue (-34.5% vs 33.1% per year).
  • The company is unprofitable; at its current free-cash-flow burn it has roughly 2.4 years of cash runway.
Revenue & net income
-$218M $79M $377M $0 2017 2018 2019 2020 2021 2022 2023 2024 2025
RevenueNet income
Margins (gross / operating / net)
-551% -250% 51% 0% 2017 2018 2019 2020 2021 2022 2023 2024 2025
GrossOperatingNet
Return on equity & assets (ROE / ROA)
-71% -13% 44% 0% 2017 2018 2019 2020 2021 2022 2023 2024 2025
ROEROA
Free cash flow (CFO − capex)
-$226M -$113M $0 2017 2018 2019 2020 2021 2022 2023 2024 2025
Free cash flow
Cash vs total debt
$0 $233M $466M 2017 2018 2019 2020 2021 2022 2023 2024 2025
CashTotal debt
Cash flow: operating / investing / financing
-$233M $48M $329M $0 2017 2018 2019 2020 2021 2022 2023 2024 2025
OperatingInvestingFinancing

Key annual figures

FYRevenueNet incomeGross MOp MROEROAFCFTotal debtCash
2025 $377M -$78M 50.7% -36.2% -16.4% -12.1% -$76M $183M
2024 $313M -$209M 42.6% -70.6% -44.2% -34.0% -$69M $226M
2023 $245M -$205M 36.6% -88.6% -32.8% -26.4% -$170M $286M
2022 $204M -$218M 41.4% -115.3% -27.6% -22.7% -$226M $379M
2021 $132M -$152M 39.1% -115.4% -26.2% -21.7% -$139M $466M
2020 $90M -$140M 31.8% -155.5% -41.6% -35.1% -$152M $4M $94M
2019 $54M -$108M 12.8% -200.1% -70.8% -57.6% -$103M $8M $47M
2018 $25M -$71M -26.6% -277.5% 35.4% -61.5% -$70M $10M $81M
2017 $11M -$59M -123.1% -543.2% 44.5% -$58M $31M

Valuation over time

How the market has priced TWST against its own fundamentals since 2023-03 — each month-end's share price set against the most recent annual filing, so the multiple moves as price runs ahead of (or behind) earnings. Split-adjusted.

Price / sales (P/S)
0.0 11.6 23.1 Mar '23 Sep '23 Mar '24 Sep '24 Mar '25 Sep '25 Mar '26 Sep '26
P/S

Frequently asked questions

Is TWST growing its revenue and profit?

Over the past 5 years, Twist Bioscience Corp's revenue has grown 33.1% per year. These are computed facts, not advice.

How much debt does TWST have?

As of FY2025, Twist Bioscience Corp reported — of total debt against $183M of cash.

What is TWST's profit margin?

In FY2025, gross margin was 50.7%, operating margin -36.2%, and net margin -20.6%.

Where does this data come from?

All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.

Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted · growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price against the latest annual filing. Informational only — not investment advice.