6 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has grown 57.5% per year over the past 5 years.
Financial health
The company holds more cash ($320M) than total debt ($50M).
Total debt has grown slower than revenue (7.7% vs 57.5% per year).
Operating income covered interest expense -1753.9× in the latest year.
The company is unprofitable; at its current free-cash-flow burn it has roughly 3.4 years of cash runway.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
2025
$10M
-$109M
0.0%
-1130.6%
-44.1%
-31.7%
-$94M
$50M
$320M
2024
$8M
-$89M
0.0%
-1097.6%
-124.8%
-55.7%
-$82M
$44M
$139M
2023
$15M
-$112M
0.0%
-468.8%
-148.9%
-64.6%
-$77M
$41M
$144M
2022
$3M
-$166M
0.0%
-6492.7%
-17493.6%
-131.5%
-$109M
$38M
$88M
2021
—
-$175M
—
—
-183.0%
-81.6%
-$132M
$37M
$149M
2020
—
-$60M
—
—
-23.9%
-23.2%
-$31M
—
$251M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
Jun '26
$0
-$47M
—
—
-12.0%
-9.9%
-$40M
$49M
$455M
Mar '26
$0
-$42M
—
—
-20.0%
-14.1%
-$41M
$49M
$277M
Dec '25
$5M
-$28M
0.0%
-516.0%
-11.3%
-8.1%
-$27M
$50M
$320M
Sep '25
$0
-$33M
—
—
-14.9%
-10.3%
-$24M
$51M
$297M
Jun '25
$2M
-$27M
0.0%
-1347.1%
-10.8%
-8.1%
-$20M
$41M
$313M
Mar '25
$2M
-$22M
0.0%
-930.5%
-39.1%
-15.6%
-$22M
$42M
$117M
Dec '24
$2M
-$19M
0.0%
-985.8%
-26.3%
-11.7%
-$18M
$44M
$139M
Sep '24
$2M
-$26M
0.0%
-1448.4%
-28.7%
-14.2%
-$22M
$43M
$158M
Jun '24
$1M
-$21M
0.0%
-1915.4%
-19.2%
-10.4%
-$22M
$38M
$173M
Mar '24
$3M
-$24M
0.0%
-713.3%
-44.7%
-15.7%
-$20M
$41M
$124M
Dec '23
$4M
$48M
0.0%
-450.8%
63.7%
27.6%
-$16M
$41M
$144M
Sep '23
$5M
-$117M
0.0%
-342.4%
238.4%
-59.8%
-$18M
$39M
$164M
Jun '23
$2M
-$25M
0.0%
-976.4%
66.3%
-30.2%
-$19M
$38M
$45M
Mar '23
$5M
-$18M
0.0%
-351.9%
117.9%
-17.3%
-$24M
$38M
$63M
Dec '22
—
-$55M
—
—
-5803.8%
-43.6%
$12M
$38M
$88M
Sep '22
—
-$27M
—
—
-247.8%
-23.8%
-$31M
$38M
$34M
Jun '22
—
-$34M
—
—
-104.9%
-24.0%
-$41M
$38M
$66M
Mar '22
—
-$50M
—
—
-99.2%
-30.3%
-$49M
$37M
$97M
Dec '21
—
-$50M
—
—
-52.8%
-23.5%
-$49M
$37M
$149M
Sep '21
—
-$51M
—
—
-36.5%
-21.2%
-$35M
$28M
$189M
Valuation over time
How the market has priced TSHA against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has risen from 104.7× (Mar '23) to 185.7× (Sep '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is TSHA growing its revenue and profit?
Over the past 5 years, Taysha Gene Therapies, Inc.'s revenue has grown 57.5% per year. These are computed facts, not advice.
How much debt does TSHA have?
As of FY2025, Taysha Gene Therapies, Inc. reported $50M of total debt against $320M of cash; operating income covered interest expense -1753.9×.
What is TSHA's profit margin?
In FY2025, gross margin was —, operating margin -1130.6%, and net margin -1115.3%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.