15 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has declined 3.5% per year over the past 5 years.
Operating margin has contracted, at -10.4% in the latest year.
Financial health
Total debt has grown slower than revenue (-48.2% vs -3.5% per year).
The company is unprofitable; at its current free-cash-flow burn it has roughly 1.1 years of cash runway.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
2025
$53M
-$7M
48.8%
-10.4%
-$14M
—
$15M
2024
$53M
$3M
54.5%
7.3%
$7M
—
$20M
2023
$65M
$8M
64.9%
16.0%
-$2M
—
$24M
2022
$48M
-$15M
58.9%
-27.3%
-$26M
—
$17M
2021
$38M
-$28M
57.4%
-53.4%
-$12M
—
$39M
2020
$63M
-$7M
82.7%
4.3%
-$27M
—
$18M
2019
$55M
-$18M
80.1%
-19.6%
-$20M
—
$18M
2018
$34M
-$26M
72.8%
-56.4%
-$8M
—
$38M
2017
$21M
-$83M
19.0%
-163.8%
-$11M
—
$51M
2016
$9M
-$29M
8.7%
-360.5%
-$33M
—
$63M
2015
$4M
$58M
83.3%
-542.4%
-$25M
—
$76M
2014
$4M
-$30M
82.1%
-810.6%
-$30M
$912000
$55M
2013
$0
-$28M
—
—
-$33M
$2M
$86M
2012
$35M
-$12M
75.4%
-34.9%
-$1M
$5M
$52M
2011
$8M
-$37M
17.2%
-435.6%
-$29M
$7M
$27M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
Mar '26
$34M
$18M
87.8%
62.7%
$21M
—
$41M
Dec '25
$9M
-$6M
49.4%
-51.1%
$2M
—
$15M
Sep '25
$18M
$2M
53.4%
11.9%
-$4M
—
$14M
Jun '25
$16M
$164000
62.5%
7.5%
-$6M
—
$18M
Mar '25
$10M
-$4M
19.1%
-41.0%
-$5M
—
$19M
Dec '24
$18M
$6M
78.7%
39.6%
$4M
—
$20M
Sep '24
$18M
$3M
53.4%
22.2%
$4M
—
$27M
Jun '24
$13M
-$2M
29.8%
-18.0%
-$4M
—
$23M
Mar '24
$4M
-$5M
30.6%
-129.6%
$4M
—
$27M
Dec '23
$10M
-$6M
15.5%
-53.5%
$3M
—
$24M
Sep '23
$10M
-$2M
52.7%
-18.2%
-$7M
—
$20M
Jun '23
$35M
$19M
82.5%
58.2%
$5M
—
$48M
Mar '23
$10M
-$3M
67.8%
-25.6%
-$3M
—
$33M
Dec '22
$9M
-$4M
72.2%
-29.0%
-$3M
—
$17M
Sep '22
$14M
-$4M
50.1%
-22.0%
-$9M
—
$11M
Jun '22
$9M
-$5M
53.3%
-63.1%
-$7M
—
$12M
Mar '22
$16M
-$2M
62.5%
-11.6%
-$6M
—
$17M
Dec '21
$9M
-$7M
63.2%
-66.7%
-$6M
—
$39M
Sep '21
$12M
-$4M
69.3%
-15.6%
-$2M
—
$11M
Jun '21
$6M
-$11M
26.4%
-142.6%
$6M
—
$34M
Valuation over time
How the market has priced PLX against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-earnings ratio has risen from 14.2× (Jan '24) to 49.2× (Nov '25).
The price-to-sales ratio has fallen from 3.6× (Mar '23) to 3.4× (Jun '26).
Price / earnings (P/E)
P/E
Price / sales (P/S)
P/S
Frequently asked questions
Is PLX growing its revenue and profit?
Over the past 5 years, Protalix BioTherapeutics, Inc.'s revenue has declined 3.5% per year. These are computed facts, not advice.
How much debt does PLX have?
As of FY2025, Protalix BioTherapeutics, Inc. reported — of total debt against $15M of cash.
What is PLX's profit margin?
In FY2025, gross margin was 48.8%, operating margin -10.4%, and net margin -12.5%.
What is PLX's P/E ratio?
As of Jun '26, Protalix BioTherapeutics, Inc. traded at a price-to-earnings ratio of about 49.2× (market cap ÷ latest annual net income). The valuation charts above show how its P/E, P/S have moved with the share price. These are computed facts, not advice.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.