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PLX Financials Protalix BioTherapeutics, Inc.

15 years of revenue, profit, cash flow and balance-sheet history through FY2025, from SEC filings — with a computed, factual read of the trend. Updated Overview →

Growth & profitability

  • Revenue has declined 3.5% per year over the past 5 years.
  • Operating margin has contracted, at -10.4% in the latest year.

Financial health

  • Total debt has grown slower than revenue (-48.2% vs -3.5% per year).
  • The company is unprofitable; at its current free-cash-flow burn it has roughly 1.1 years of cash runway.
Revenue & net income
-$83M -$9M $65M $0 2011 2013 2015 2017 2019 2021 2023 2025
RevenueNet income
Margins (gross / operating / net)
-850% 240% 1330% 0% 2011 2013 2015 2017 2019 2021 2023 2025
GrossOperatingNet
Return on equity & assets (ROE / ROA)
-116% 209% 534% 0% 2011 2013 2015 2017 2019 2021 2023 2025
ROEROA
Free cash flow (CFO − capex)
-$33M -$13M $7M $0 2011 2013 2015 2017 2019 2021 2023 2025
Free cash flow
Cash vs total debt
$0 $43M $86M 2011 2013 2015 2017 2019 2021 2023 2025
CashTotal debt
Cash flow: operating / investing / financing
-$32M $7M $46M $0 2011 2013 2015 2017 2019 2021 2023 2025
OperatingInvestingFinancing

Key annual figures

FYRevenueNet incomeGross MOp MROEROAFCFTotal debtCash
2025 $53M -$7M 48.8% -10.4% -13.7% -8.0% -$14M — $15M
2024 $53M $3M 54.5% 7.3% 6.8% 4.0% $7M — $20M
2023 $65M $8M 64.9% 16.0% 24.8% 9.8% -$2M — $24M
2022 $48M -$15M 58.9% -27.3% 140.3% -26.8% -$26M — $17M
2021 $38M -$28M 57.4% -53.4% 457.0% -37.4% -$12M — $39M
2020 $63M -$7M 82.7% 4.3% 24.1% -9.6% -$27M — $18M
2019 $55M -$18M 80.1% -19.6% 26.0% -40.3% -$20M — $18M
2018 $34M -$26M 72.8% -56.4% 50.0% -43.3% -$8M — $38M
2017 $21M -$83M 19.0% -163.8% 283.3% -115.5% -$11M — $51M
2016 $9M -$29M 8.7% -360.5% 294.9% -35.7% -$33M — $63M
2015 $4M $58M 83.3% -542.4% 533.8% 59.7% -$25M — $76M
2014 $4M -$30M 82.1% -810.6% 53.9% -38.2% -$30M $912000 $55M
2013 $0 -$28M — — 103.1% -24.5% -$33M $2M $86M
2012 $35M -$12M 75.4% -34.9% 346.1% -14.8% -$1M $5M $52M
2011 $8M -$37M 17.2% -435.6% 140.1% -70.5% -$29M $7M $27M

Valuation over time

How the market has priced PLX against its own fundamentals since 2023-03 — each month-end's share price set against the most recent annual filing, so the multiple moves as price runs ahead of (or behind) earnings. Split-adjusted.

Price / earnings (P/E)
0.0 42.1 84.2 Mar '23 Sep '23 Mar '24 Sep '24 Mar '25 Sep '25 Mar '26 Sep '26
P/E
Price / sales (P/S)
0.0 2.3 4.7 Mar '23 Sep '23 Mar '24 Sep '24 Mar '25 Sep '25 Mar '26 Sep '26
P/S

Frequently asked questions

Is PLX growing its revenue and profit?

Over the past 5 years, Protalix BioTherapeutics, Inc.'s revenue has declined 3.5% per year. These are computed facts, not advice.

How much debt does PLX have?

As of FY2025, Protalix BioTherapeutics, Inc. reported — of total debt against $15M of cash.

What is PLX's profit margin?

In FY2025, gross margin was 48.8%, operating margin -10.4%, and net margin -12.5%.

What is PLX's P/E ratio?

Protalix BioTherapeutics, Inc.'s P/E (TTM) is 11.08 as of the 2026-11-03 close — market cap ÷ net income over the trailing twelve months where four consecutive quarters are reported, otherwise the latest fiscal year, the same figure as on the PLX stock page. The valuation chart above sets each month-end's price against the latest annual net income instead, so its latest point (about 49.2× as of Nov '26) can differ. These are computed facts, not advice.

Where does this data come from?

All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.

Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), split-adjusted; price return — dividends not reinvested · growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price against the latest annual filing. Informational only — not investment advice.