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PBYI Financials PUMA BIOTECHNOLOGY, INC.

15 years of revenue, profit, cash flow and balance-sheet history through FY2025, from SEC filings — with a computed, factual read of the trend. Updated Overview →

Growth & profitability

  • Revenue has grown 0.3% per year over the past 5 years.
  • Operating margin has expanded, at 16.3% in the latest year.
  • Free cash flow has grown 124.8% per year over the past 5 years.

Financial health

  • The company holds more cash ($30M) than total debt ($23M).
  • Total debt has grown slower than revenue (-23.0% vs 0.3% per year).
  • Operating income covered interest expense 5.6× in the latest year.
  • Total debt is 0.5× EBITDA.
Revenue & net income
-$292M -$10M $272M $0 2014 2014 2015 2017 2019 2021 2023 2025
RevenueNet income
Margins (gross / operating / net)
-1056% -485% 86% 0% 2014 2014 2015 2017 2019 2021 2023 2025
GrossOperatingNet
Free cash flow (CFO − capex)
-$173M -$66M $42M $0 2014 2014 2015 2017 2019 2021 2023 2025
Free cash flow
Cash vs total debt
$0 $97M $194M 2014 2014 2015 2017 2019 2021 2023 2025
CashTotal debt
Cash flow: operating / investing / financing
-$172M -$5M $162M $0 2014 2014 2015 2017 2019 2021 2023 2025
OperatingInvestingFinancing

Key annual figures

FYRevenueNet incomeGross MOp MFCFTotal debtCash
2025 $228M $31M 74.5% 16.3% $42M $23M $30M
2024 $230M $30M 72.1% 13.4% $39M $68M $69M
2023 $236M $22M 73.4% 13.9% $27M $102M $85M
2022 $228M $2000 75.8% 10.4% -$16M $102M $76M
2021 $253M $29M 74.8% 0.5% $21M $102M $63M
2020 $225M -$60M 82.5% -13.5% $727000 $84M $85M
2019 $272M -$76M 86.5% -14.3% $22M $95M $60M
2018 $251M -$114M 86.2% -37.7% -$25M $152M $108M
2017 $28M -$292M 79.9% -1056.1% -$173M $48M $82M
2016 -$276M -$146M $194M
2015 -$239M $32M
2014 -$142M $39M
2014 -$234M $28M
2014 -$198M $55M
2014 -$159M $163M

Valuation over time

How the market has priced PBYI against its own fundamentals since 2023-03 — each month-end's share price set against the most recent annual filing, so the multiple moves as price runs ahead of (or behind) earnings. Split-adjusted.

Price / earnings (P/E)
0.0 55225.9 110451.8 Mar '23 Aug '23 Jan '24 Jun '24 Nov '24 Apr '25 Sep '25 Feb '26
P/E
Price / sales (P/S)
0.0 0.9 1.7 Mar '23 Aug '23 Jan '24 Jun '24 Nov '24 Apr '25 Sep '25 Feb '26
P/S

Frequently asked questions

Is PBYI growing its revenue and profit?

Over the past 5 years, PUMA BIOTECHNOLOGY, INC.'s revenue has grown 0.3% per year. These are computed facts, not advice.

How much debt does PBYI have?

As of FY2025, PUMA BIOTECHNOLOGY, INC. reported $23M of total debt against $30M of cash; operating income covered interest expense 5.6×.

What is PBYI's profit margin?

In FY2025, gross margin was 74.5%, operating margin 16.3%, and net margin 13.6%.

What is PBYI's P/E ratio?

As of Jun '26, PUMA BIOTECHNOLOGY, INC. traded at a price-to-earnings ratio of about 12.6× (market cap ÷ latest annual net income). The valuation charts above show how its P/E, P/S have moved with the share price. These are computed facts, not advice.

Where does this data come from?

All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.

Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted · growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price against the latest annual filing. Informational only — not investment advice.