15 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has grown 0.3% per year over the past 5 years.
Operating margin has expanded, at 16.3% in the latest year.
Free cash flow has grown 124.8% per year over the past 5 years.
Financial health
The company holds more cash ($30M) than total debt ($23M).
Total debt has grown slower than revenue (-23.0% vs 0.3% per year).
Operating income covered interest expense 5.6× in the latest year.
Total debt is 0.5× EBITDA.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
2025
$228M
$31M
74.5%
16.3%
$42M
$23M
$30M
2024
$230M
$30M
72.1%
13.4%
$39M
$68M
$69M
2023
$236M
$22M
73.4%
13.9%
$27M
$102M
$85M
2022
$228M
$2000
75.8%
10.4%
-$16M
$102M
$76M
2021
$253M
$29M
74.8%
0.5%
$21M
$102M
$63M
2020
$225M
-$60M
82.5%
-13.5%
$727000
$84M
$85M
2019
$272M
-$76M
86.5%
-14.3%
$22M
$95M
$60M
2018
$251M
-$114M
86.2%
-37.7%
-$25M
$152M
$108M
2017
$28M
-$292M
79.9%
-1056.1%
-$173M
$48M
$82M
2016
—
-$276M
—
—
-$146M
—
$194M
2015
—
-$239M
—
—
—
—
$32M
2014
—
-$142M
—
—
—
—
$39M
2014
—
-$234M
—
—
—
—
$28M
2014
—
-$198M
—
—
—
—
$55M
2014
—
-$159M
—
—
—
—
$163M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
Mar '26
$45M
-$4M
76.7%
-8.5%
$15M
$11M
$36M
Dec '25
$75M
$13M
69.3%
22.7%
$14M
$23M
$30M
Sep '25
$54M
$9M
77.7%
17.6%
$10M
$34M
$54M
Jun '25
$52M
$6M
76.5%
12.7%
$14M
$45M
$55M
Mar '25
$46M
$3M
77.1%
8.7%
$4M
$57M
$63M
Dec '24
$59M
$19M
76.4%
22.6%
$16M
$68M
$69M
Sep '24
$81M
$20M
63.9%
27.4%
$11M
$79M
$67M
Jun '24
$47M
-$5M
77.4%
-4.6%
$1M
$91M
$67M
Mar '24
$44M
-$5M
75.5%
-5.3%
$11M
$102M
$77M
Dec '23
$72M
$12M
66.3%
20.5%
$10M
$102M
$85M
Sep '23
$56M
$6M
76.3%
15.3%
$11M
$102M
$82M
Jun '23
$55M
$2M
78.3%
9.0%
—
$102M
$60M
Mar '23
$53M
$1M
75.0%
8.3%
—
$102M
$61M
Dec '22
$66M
-$6M
74.4%
15.3%
$8M
$102M
$76M
Sep '22
$57M
-$360000
78.1%
4.2%
$17M
$102M
$78M
Jun '22
$60M
$9M
74.9%
20.3%
—
$102M
$53M
Mar '22
$46M
-$3M
76.3%
-1.6%
—
$102M
$64M
Dec '21
$55M
$4M
78.5%
12.3%
-$5M
$102M
$63M
Sep '21
$46M
-$45M
77.8%
-19.4%
—
$102M
$64M
Jun '21
$53M
-$5M
77.6%
-31.2%
—
$69M
$90M
Valuation over time
How the market has priced PBYI against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-earnings ratio has fallen from 78639.7× (Mar '23) to 12.6× (Jun '26).
The price-to-sales ratio has risen from 0.7× (Mar '23) to 1.7× (Jun '26).
Price / earnings (P/E)
P/E
Price / sales (P/S)
P/S
Frequently asked questions
Is PBYI growing its revenue and profit?
Over the past 5 years, PUMA BIOTECHNOLOGY, INC.'s revenue has grown 0.3% per year. These are computed facts, not advice.
How much debt does PBYI have?
As of FY2025, PUMA BIOTECHNOLOGY, INC. reported $23M of total debt against $30M of cash; operating income covered interest expense 5.6×.
What is PBYI's profit margin?
In FY2025, gross margin was 74.5%, operating margin 16.3%, and net margin 13.6%.
What is PBYI's P/E ratio?
As of Jun '26, PUMA BIOTECHNOLOGY, INC. traded at a price-to-earnings ratio of about 12.6× (market cap ÷ latest annual net income). The valuation charts above show how its P/E, P/S have moved with the share price. These are computed facts, not advice.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.