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OPK Financials OPKO HEALTH, INC.

15 years of revenue, profit, cash flow and balance-sheet history through FY2025, from SEC filings — with a computed, factual read of the trend. Updated Overview →

Growth & profitability

  • Revenue has declined 15.8% per year over the past 5 years.
  • Operating margin has contracted, at -19.3% in the latest year.

Financial health

  • The company holds more cash ($364M) than total debt ($344M).
  • Total debt has grown faster than revenue (6.5% vs -15.8% per year).
  • The company is unprofitable; at its current free-cash-flow burn it has roughly 1.9 years of cash runway.
Revenue & net income
-$328B -$163B $2B $0 2011 2013 2015 2017 2019 2021 2023 2025
RevenueNet income
Margins (gross / operating / net)
-37187% -18569% 50% 0% 2011 2013 2015 2017 2019 2021 2023 2025
GrossOperatingNet
Free cash flow (CFO − capex)
-$208M -$28M $153M $0 2011 2013 2015 2017 2019 2021 2023 2025
Free cash flow
Cash vs total debt
$0 $219M $437M 2011 2013 2015 2017 2019 2021 2023 2025
CashTotal debt
Cash flow: operating / investing / financing
-$183M $84M $352M $0 2011 2013 2015 2017 2019 2021 2023 2025
OperatingInvestingFinancing

Key annual figures

FYRevenueNet incomeGross MOp MFCFTotal debtCash
2025 $607M -$225.7B 33.9% -19.3% -$191M $344M $364M
2024 $713M -$53.2B 30.6% -21.3% -$208M $437M $427M
2023 $863M -$188.9B 36.8% -18.2% -$44M $50600 $96M
2022 $1.0B -$328.4B 28.7% -22.5% -$120M $256M $153M
2021 $1.8B -$30.1B 0.0% 1.1% $6M $205M $135M
2020 $1.4B $31M 0.0% 4.0% $6M $251M $72M
2019 $902M -$315M 0.0% -30.4% -$185M $270M $85M
2018 $990M -$153M 0.0% -17.3% -$137M $11M $96M
2017 $966M -$305M 0.0% -28.6% -$139M $13M $91M
2016 $1.1B -$48M 49.5% -8.6% $13M $13M $169M
2015 $305M -$52M 36.7% -39.5% $153M $14M $194M
2014 -$172M -$95M $16M $97M
2013 -$114M -$60M $16M $186M
2012 -$29M -$27M $5M $27M
2011 -$1M -$20M $72M

Valuation over time

How the market has priced OPK against its own fundamentals since 2023-03 — each month-end's share price set against the most recent annual filing, so the multiple moves as price runs ahead of (or behind) earnings. Split-adjusted.

Price / sales (P/S)
0.0 0.9 1.9 Mar '23 Aug '23 Jan '24 Jun '24 Nov '24 Apr '25 Sep '25 Feb '26
P/S

Frequently asked questions

Is OPK growing its revenue and profit?

Over the past 5 years, OPKO HEALTH, INC.'s revenue has declined 15.8% per year. These are computed facts, not advice.

How much debt does OPK have?

As of FY2025, OPKO HEALTH, INC. reported $344M of total debt against $364M of cash.

What is OPK's profit margin?

In FY2025, gross margin was 33.9%, operating margin -19.3%, and net margin -37187.0%.

Where does this data come from?

All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.

Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted · growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price against the latest annual filing. Informational only — not investment advice.