15 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has declined 15.8% per year over the past 5 years.
Operating margin has contracted, at -19.3% in the latest year.
Financial health
The company holds more cash ($364M) than total debt ($344M).
Total debt has grown faster than revenue (6.5% vs -15.8% per year).
The company is unprofitable; at its current free-cash-flow burn it has roughly 1.9 years of cash runway.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
2025
$607M
-$225.7B
33.9%
-19.3%
-$191M
$344M
$364M
2024
$713M
-$53.2B
30.6%
-21.3%
-$208M
$437M
$427M
2023
$863M
-$188.9B
36.8%
-18.2%
-$44M
$50600
$96M
2022
$1.0B
-$328.4B
28.7%
-22.5%
-$120M
$256M
$153M
2021
$1.8B
-$30.1B
0.0%
1.1%
$6M
$205M
$135M
2020
$1.4B
$31M
0.0%
4.0%
$6M
$251M
$72M
2019
$902M
-$315M
0.0%
-30.4%
-$185M
$270M
$85M
2018
$990M
-$153M
0.0%
-17.3%
-$137M
$11M
$96M
2017
$966M
-$305M
0.0%
-28.6%
-$139M
$13M
$91M
2016
$1.1B
-$48M
49.5%
-8.6%
$13M
$13M
$169M
2015
$305M
-$52M
36.7%
-39.5%
$153M
$14M
$194M
2014
—
-$172M
—
—
-$95M
$16M
$97M
2013
—
-$114M
—
—
-$60M
$16M
$186M
2012
—
-$29M
—
—
-$27M
$5M
$27M
2011
—
-$1M
—
—
-$20M
—
$72M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
Mar '26
$124M
-$55M
36.8%
-41.1%
-$21M
$346M
$332M
Dec '25
$148M
-$31M
43.1%
-25.8%
-$29M
$344M
$364M
Sep '25
$152M
$22M
32.9%
31.7%
-$38M
$344M
$412M
Jun '25
$157M
-$148M
31.5%
-38.3%
-$87M
$343M
$267M
Mar '25
$150M
-$68M
28.4%
-44.8%
-$38M
$439M
$429M
Dec '24
$184M
$14M
46.1%
-18.0%
-$50M
$437M
$427M
Sep '24
$174M
$25M
23.1%
-38.7%
-$85M
$441M
$400M
Jun '24
$182M
-$10M
28.4%
-33.9%
-$34M
$202M
$41M
Mar '24
$174M
-$82M
24.2%
-41.2%
-$40M
$350M
$76M
Dec '23
$182M
-$66M
0.0%
-38.0%
-$41M
$50600
$96M
Sep '23
$179M
-$84M
0.0%
-36.1%
$29M
$251M
$139M
Jun '23
$265M
-$20M
0.0%
2.6%
-$6M
$250M
$108M
Mar '23
$238M
-$18M
0.0%
-12.9%
-$26M
$245M
$111M
Dec '22
$185M
-$85M
0.0%
-29.8%
-$38M
$256M
$153M
Sep '22
$180M
-$86M
0.0%
-48.9%
-$40M
$245M
$181M
Jun '22
$310M
-$102M
0.0%
-3.5%
-$17M
$232M
$210M
Mar '22
$329M
-$55M
0.0%
-22.0%
-$25M
$230M
$102M
Dec '21
$401M
-$74M
0.0%
-15.7%
-$12M
$205M
$135M
Sep '21
$386M
$29M
0.0%
9.8%
$26M
$203M
$149M
Jun '21
$442M
-$16M
0.0%
1.3%
-$24M
$206M
$66M
Valuation over time
How the market has priced OPK against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has risen from 1.1× (Mar '23) to 1.9× (Jun '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is OPK growing its revenue and profit?
Over the past 5 years, OPKO HEALTH, INC.'s revenue has declined 15.8% per year. These are computed facts, not advice.
How much debt does OPK have?
As of FY2025, OPKO HEALTH, INC. reported $344M of total debt against $364M of cash.
What is OPK's profit margin?
In FY2025, gross margin was 33.9%, operating margin -19.3%, and net margin -37187.0%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.