10 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Financial health
Total debt ($340M) exceeds cash ($199M); net debt is $141M.
Operating income covered interest expense -13.5× in the latest year.
The company is unprofitable; at its current free-cash-flow burn it has roughly 1.0 years of cash runway.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
2025
$958M
-$288M
0.0%
-31.3%
-$190M
$340M
$199M
2024
$180M
-$466M
96.5%
-276.4%
-$457M
$118M
$100M
2023
$0
-$374M
—
—
-$326M
$115M
$100M
2022
$0
-$295M
—
—
-$225M
$70M
$332M
2021
—
-$242M
—
—
-$184M
$0
$36M
2020
—
-$202M
—
—
-$158M
—
$54M
2019
—
-$84M
—
—
-$42M
—
$47M
2018
—
-$33M
—
—
-$26M
—
$57M
2017
—
-$31M
—
—
-$22M
—
$149M
2016
—
-$26M
—
—
-$18M
—
$19M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
Mar '26
$311M
-$94M
0.0%
-29.8%
-$171M
$340M
$227M
Dec '25
$321M
-$59M
0.0%
-18.6%
-$133M
$340M
$199M
Sep '25
$287M
-$114M
0.0%
-39.7%
$79M
$340M
$296M
Jun '25
$213M
-$42M
0.0%
-22.2%
-$47M
$118M
$186M
Mar '25
$137M
-$73M
96.7%
-57.8%
-$89M
$118M
$184M
Dec '24
$103M
-$59M
0.0%
-64.8%
-$105M
$118M
$100M
Sep '24
$62M
-$107M
0.0%
-187.1%
-$68M
$117M
$233M
Jun '24
$15M
-$152M
0.0%
-1110.4%
-$135M
$117M
$495M
Mar '24
$0
-$148M
—
—
-$150M
$116M
$623M
Dec '23
$0
-$112M
—
—
-$81M
$115M
$100M
Sep '23
$0
-$99M
—
—
-$85M
$149M
$62M
Jun '23
$0
-$86M
—
—
-$75M
$132M
$77M
Mar '23
—
-$77M
—
—
-$84M
$114M
$113M
Dec '22
—
-$86M
—
—
-$59M
$70M
$332M
Sep '22
—
-$81M
—
—
-$59M
$68M
$59M
Jun '22
—
-$71M
—
—
-$57M
$67M
$53M
Mar '22
—
-$58M
—
—
-$50M
—
$42M
Dec '21
—
-$65M
—
—
-$48M
$0
$36M
Sep '21
—
-$63M
—
—
-$46M
—
$49M
Jun '21
—
-$62M
—
—
-$47M
—
$34M
Valuation over time
How the market has priced MDGL against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has fallen from 39.4× (Dec '24) to 12.4× (Jun '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is MDGL growing its revenue and profit?
See the revenue and net-income charts above for Madrigal Pharmaceuticals, Inc.'s multi-year trend.
How much debt does MDGL have?
As of FY2025, Madrigal Pharmaceuticals, Inc. reported $340M of total debt against $199M of cash; operating income covered interest expense -13.5×.
What is MDGL's profit margin?
In FY2025, gross margin was —, operating margin -31.3%, and net margin -30.1%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.