15 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has declined 61.2% per year over the past 5 years.
Operating margin has contracted, at -132871.3% in the latest year.
Financial health
The company is unprofitable and has less than a year of cash runway at its current free-cash-flow burn.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
2025
$65343
-$85M
0.0%
-132871.3%
-352.8%
-114.4%
-$89M
—
$44M
2024
$217756
-$107M
0.0%
-51616.9%
-156.2%
-94.5%
-$105M
—
$66M
2023
$832010
-$135M
0.0%
-17300.3%
-115.0%
-79.0%
-$125M
—
$14M
2022
$10M
-$280M
0.0%
-2607.4%
-125.8%
-80.3%
-$217M
—
$46M
2021
$2M
-$304M
0.0%
-16972.3%
-76.0%
-61.2%
-$217M
—
$71M
2020
$7M
-$166M
0.0%
-1674.2%
-36.1%
-30.8%
-$179M
—
$251M
2019
$4M
-$119M
0.0%
-2702.1%
-3474.7%
-82.9%
-$99M
—
$22M
2018
$30M
-$97M
0.0%
-308.7%
-111.5%
-74.0%
-$76M
$0
$24M
2017
$42M
-$88M
0.0%
-198.1%
-61.9%
-47.1%
-$74M
—
$24M
2016
$35M
-$74M
0.0%
-215.5%
-59.8%
-42.5%
-$65M
—
$19M
2015
—
-$29M
—
—
-16.6%
-13.6%
-$15M
—
$58M
2014
—
-$36M
—
—
-32.5%
-27.4%
-$31M
—
$41M
2013
—
-$66M
—
—
-125.9%
-74.8%
-$16M
—
$34M
2012
—
-$20M
—
—
-57.3%
-43.6%
-$23M
—
$6M
2011
—
-$15M
—
—
-32.2%
-25.0%
-$20M
—
$17M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
Jun '26
$0
-$6M
—
—
-137.6%
-12.2%
-$18M
—
$32M
Mar '26
$0
-$20M
—
—
-324.4%
-39.5%
-$22M
—
$26M
Dec '25
$0
$4M
—
—
15.6%
5.1%
-$19M
—
$44M
Sep '25
$0
-$45M
—
—
589.3%
-65.6%
-$22M
—
$37M
Jun '25
$0
-$24M
—
—
-82.4%
-34.5%
-$21M
—
$24M
Mar '25
$65343
-$20M
0.0%
-38337.0%
-38.4%
-22.6%
-$27M
—
$40M
Dec '24
$116994
-$19M
0.0%
-17410.8%
-28.3%
-17.1%
-$20M
—
$66M
Sep '24
$0
-$25M
—
—
-34.2%
-23.5%
-$27M
—
$22M
Jun '24
$100762
-$32M
0.0%
-32945.9%
-33.3%
-24.1%
-$29M
—
$34M
Mar '24
$0
-$30M
—
—
-32.3%
-23.6%
-$29M
—
$20M
Dec '23
$102651
-$25M
0.0%
-26686.3%
-21.3%
-14.6%
-$26M
—
$14M
Sep '23
$388446
-$34M
0.0%
-9152.6%
-24.6%
-17.6%
-$29M
—
$19M
Jun '23
$225971
-$36M
0.0%
-16392.0%
-21.0%
-15.2%
-$32M
—
$53M
Mar '23
$114943
-$41M
0.0%
-38238.2%
-20.4%
-15.2%
-$37M
—
$28M
Dec '22
$124666
-$54M
0.0%
-44876.8%
-24.5%
-15.6%
-$37M
—
$46M
Sep '22
$9M
-$38M
0.0%
-390.6%
-14.2%
-9.6%
-$68M
—
$22M
Jun '22
$784395
-$108M
0.0%
-13276.1%
-36.4%
-23.6%
-$51M
—
$41M
Mar '22
$199074
-$79M
0.0%
-36033.3%
-22.3%
-17.7%
-$62M
—
$59M
Dec '21
$839115
-$107M
0.0%
-12573.8%
-26.8%
-21.6%
-$39M
—
$71M
Sep '21
$291698
-$60M
0.0%
-20553.2%
-13.3%
-11.2%
-$47M
—
$68M
Valuation over time
How the market has priced INO against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has risen from 8.3× (Mar '23) to 2144.1× (Sep '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is INO growing its revenue and profit?
Over the past 5 years, INOVIO PHARMACEUTICALS, INC.'s revenue has declined 61.2% per year. These are computed facts, not advice.
How much debt does INO have?
As of FY2025, INOVIO PHARMACEUTICALS, INC. reported — of total debt against $44M of cash.
What is INO's profit margin?
In FY2025, gross margin was —, operating margin -132871.3%, and net margin -130082.8%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.