13 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has grown 2.2% per year over the past 5 years.
Operating margin has expanded, at -29.3% in the latest year.
Financial health
The company is unprofitable and has less than a year of cash runway at its current free-cash-flow burn.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
2025
$76M
-$17M
0.0%
-29.3%
-17.5%
-11.5%
-$76M
—
$13M
2024
$138M
$32M
0.0%
18.1%
-6988.8%
26.4%
-$87M
—
$38M
2023
$101M
-$569000
0.0%
-6.4%
1.2%
-0.3%
-$57M
—
$17M
2022
$53M
-$99M
0.0%
-190.6%
115.8%
-38.1%
-$113M
—
$194M
2021
$37M
-$116M
0.0%
-311.0%
25244.0%
-34.1%
-$121M
—
$206M
2020
$68M
-$65M
0.0%
-117.7%
833.8%
-18.1%
$3M
—
$192M
2019
$27M
-$133M
0.0%
-525.9%
-521.5%
-38.9%
-$144M
—
$188M
2018
$60M
-$85M
0.0%
-130.9%
-62.3%
-18.5%
-$79M
—
$248M
2017
$72M
-$43M
0.0%
-64.6%
-61.7%
-10.8%
$169M
—
$178M
2016
$13M
-$59M
0.0%
-463.9%
-75.1%
-29.6%
-$4M
—
$105M
2015
—
-$35M
—
—
-28.1%
-17.9%
—
—
$60M
2014
—
-$30M
—
—
38.6%
-41.5%
—
$3M
$64M
2013
—
-$15M
—
—
34.2%
—
—
—
$9M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
Jun '26
$1M
-$21M
0.0%
-1677.1%
-6.8%
-5.4%
-$18M
—
$17M
Mar '26
$10M
-$18M
0.0%
-191.8%
-5.7%
-5.1%
-$26M
—
$29M
Dec '25
$663000
-$27M
0.0%
-4213.0%
-26.8%
-17.5%
-$23M
—
$13M
Sep '25
$6M
-$14M
0.0%
-264.4%
-13.2%
-9.0%
-$15M
—
$34M
Jun '25
$19M
-$154000
0.0%
-6.9%
-0.1%
-0.1%
-$16M
—
$49M
Mar '25
$51M
$24M
0.0%
44.4%
93.9%
23.9%
-$21M
—
$48M
Dec '24
$38M
$19M
0.0%
46.4%
-4139.5%
15.7%
-$20M
—
$38M
Sep '24
$33M
$6M
0.0%
12.3%
-24.5%
4.1%
-$21M
—
$41M
Jun '24
$25M
-$7M
0.0%
-33.7%
20.9%
-4.1%
-$20M
—
$43M
Mar '24
$41M
$14M
0.0%
28.1%
-43.5%
7.5%
-$26M
—
$36M
Dec '23
$27M
$837000
0.0%
-2.3%
-1.8%
0.4%
-$22M
—
$17M
Sep '23
$26M
$3M
0.0%
11.8%
-5.8%
1.4%
-$18M
—
$26M
Jun '23
$25M
-$1M
0.0%
-13.5%
1.3%
-0.5%
-$26M
—
$58M
Mar '23
$23M
-$3M
0.0%
-24.1%
3.8%
-1.4%
$9M
—
$56M
Dec '22
$20M
-$9M
0.0%
-47.2%
10.2%
-3.4%
-$2M
—
$194M
Sep '22
$11M
-$29M
0.0%
-266.5%
36.1%
-12.8%
-$34M
—
$95M
Jun '22
$13M
-$29M
0.0%
-233.8%
54.1%
-11.3%
-$35M
—
$129M
Mar '22
$9M
-$32M
0.0%
-354.7%
107.5%
-10.8%
-$42M
—
$163M
Dec '21
-$13M
-$58M
0.0%
467.3%
12742.7%
-17.2%
-$31M
—
$206M
Sep '21
$18M
-$23M
0.0%
-128.7%
-74.2%
-6.1%
-$30M
—
$236M
Valuation over time
How the market has priced CTMX against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-earnings ratio has risen from 7.0× (Dec '24) to 29.2× (Nov '25).
The price-to-sales ratio has risen from 6.2× (Mar '23) to 10.5× (Sep '26).
Price / earnings (P/E)
P/E
Price / sales (P/S)
P/S
Frequently asked questions
Is CTMX growing its revenue and profit?
Over the past 5 years, Cytomx Therapeutics, Inc.'s revenue has grown 2.2% per year. These are computed facts, not advice.
How much debt does CTMX have?
As of FY2025, Cytomx Therapeutics, Inc. reported — of total debt against $13M of cash.
What is CTMX's profit margin?
In FY2025, gross margin was —, operating margin -29.3%, and net margin -22.8%.
What is CTMX's P/E ratio?
As of Sep '26, Cytomx Therapeutics, Inc. traded at a price-to-earnings ratio of about 29.2× (market cap ÷ latest annual net income). The valuation charts above show how its P/E, P/S have moved with the share price. These are computed facts, not advice.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.