8 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has grown 40.6% per year over the past 5 years.
Operating margin has contracted, at -12.4% in the latest year.
Free cash flow has grown 40.8% per year over the past 5 years.
Financial health
The company holds more cash ($117M) than total debt ($10M).
Operating income covered interest expense -497.8× in the latest year.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
2025
$344M
-$24M
79.4%
-12.4%
$28M
$10M
$117M
2024
$332M
$18M
81.9%
2.6%
$37M
$10M
$120M
2023
$220M
-$57M
79.5%
-30.9%
-$19M
$0
$99M
2022
$137M
-$67M
76.6%
-53.2%
-$47M
—
$123M
2021
$94M
-$31M
83.2%
-42.6%
-$22M
—
$330M
2020
$63M
-$10M
84.5%
-10.4%
$5M
$0
$410M
2019
$52M
$5M
85.9%
14.1%
$6M
$27M
$99M
2018
$23M
-$6M
76.8%
-16.8%
-$13M
$25M
$4M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
Mar '26
$84M
-$15M
75.5%
-22.0%
-$35M
$10M
$64M
Dec '25
$87M
-$2M
79.0%
-4.4%
$20M
$10M
$117M
Sep '25
$83M
-$501000
77.5%
-8.2%
$8M
$10M
$86M
Jun '25
$86M
$5M
79.5%
-4.9%
$12M
$10M
$82M
Mar '25
$88M
-$26M
81.4%
-31.7%
-$11M
$10M
$90M
Dec '24
$86M
$10M
81.3%
4.7%
$17M
$10M
$120M
Sep '24
$86M
$2M
81.8%
5.9%
$17M
$10M
$95M
Jun '24
$87M
$9M
83.3%
5.8%
$19M
$10M
$86M
Mar '24
$73M
-$3M
81.0%
-7.5%
-$16M
$10M
$83M
Dec '23
$66M
-$3M
81.2%
-8.6%
$15M
$0
$99M
Sep '23
$61M
-$7M
81.6%
-15.7%
$3M
—
$91M
Jun '23
$50M
-$19M
77.9%
-42.2%
-$8M
—
$96M
Mar '23
$42M
-$29M
75.8%
-75.0%
-$29M
$0
$115M
Dec '22
$38M
-$21M
75.2%
-59.6%
-$8M
—
$123M
Sep '22
$37M
-$20M
76.1%
-58.2%
-$7M
—
$134M
Jun '22
$35M
-$2M
77.9%
-11.4%
-$10M
—
$273M
Mar '22
$27M
-$25M
77.9%
-91.3%
-$22M
—
$309M
Dec '21
$25M
-$6M
81.6%
-60.6%
-$4M
—
$330M
Sep '21
$23M
-$12M
80.8%
-50.3%
-$7M
—
$363M
Jun '21
$23M
-$9M
83.8%
-38.7%
-$7M
—
$368M
Valuation over time
How the market has priced CSTL against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-earnings ratio has risen from 44.3× (Dec '24) to 69.8× (Nov '25).
The price-to-sales ratio has fallen from 5.0× (Mar '23) to 2.0× (Jun '26).
Price / earnings (P/E)
P/E
Price / sales (P/S)
P/S
Frequently asked questions
Is CSTL growing its revenue and profit?
Over the past 5 years, CASTLE BIOSCIENCES INC's revenue has grown 40.6% per year. These are computed facts, not advice.
How much debt does CSTL have?
As of FY2025, CASTLE BIOSCIENCES INC reported $10M of total debt against $117M of cash; operating income covered interest expense -497.8×.
What is CSTL's profit margin?
In FY2025, gross margin was 79.4%, operating margin -12.4%, and net margin -7.0%.
What is CSTL's P/E ratio?
As of Jun '26, CASTLE BIOSCIENCES INC traded at a price-to-earnings ratio of about 69.8× (market cap ÷ latest annual net income). The valuation charts above show how its P/E, P/S have moved with the share price. These are computed facts, not advice.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.