10 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has grown 155.3% per year over the past 5 years.
Operating margin has expanded, at -6714.8% in the latest year.
Financial health
The company is unprofitable and has less than a year of cash runway at its current free-cash-flow burn.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
2025
$8M
-$465M
86.0%
-6714.8%
-$384M
—
$102M
2024
$1M
-$298M
100.0%
-32613.5%
-$234M
—
$265M
2023
$4M
-$215M
100.0%
-5547.2%
-$173M
—
$55M
2022
$0
-$164M
—
—
-$117M
—
$33M
2021
$0
-$108M
—
—
-$89M
—
$201M
2020
$71000
-$74M
0.0%
-105567.6%
-$62M
—
$93M
2019
$1M
-$50M
0.0%
-4512.3%
-$47M
—
$40M
2018
$2M
-$27M
0.0%
-1182.5%
-$21M
—
$45M
2017
$2M
-$9M
0.0%
-446.3%
-$10M
—
$14M
2016
$589000
-$6M
0.0%
-1026.1%
-$6M
—
—
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
Mar '26
$11M
-$128M
98.1%
-1307.8%
-$126M
—
$114M
Dec '25
$6M
-$123M
0.0%
-2169.6%
-$93M
—
$102M
Sep '25
$143000
-$130M
0.0%
-99710.5%
-$112M
—
$111M
Jun '25
$1M
-$116M
0.0%
-12523.0%
-$89M
—
$54M
Mar '25
$361000
-$97M
100.0%
-30860.1%
-$90M
—
$95M
Dec '24
$0
-$81M
—
—
-$68M
—
$265M
Sep '24
$0
-$77M
—
—
-$63M
—
$317M
Jun '24
$399000
-$74M
0.0%
-20747.6%
-$49M
—
$302M
Mar '24
$640000
-$67M
0.0%
-11488.9%
-$54M
—
$396M
Dec '23
—
-$60M
—
—
-$39M
—
$55M
Sep '23
$346000
-$57M
0.0%
-17045.4%
-$45M
—
$143M
Jun '23
$988000
-$51M
0.0%
-5363.9%
-$46M
—
$40M
Mar '23
$3M
-$46M
0.0%
-1790.9%
-$41M
—
$41M
Dec '22
-$4M
-$45M
0.0%
1180.6%
-$35M
—
$33M
Sep '22
$458000
-$42M
0.0%
-9487.8%
-$39M
—
$31M
Jun '22
$439000
-$42M
0.0%
-9805.2%
-$29M
—
$62M
Mar '22
$3M
-$35M
0.0%
-1080.4%
-$14M
—
$146M
Dec '21
$0
-$31M
—
—
-$23M
—
$201M
Sep '21
$0
-$28M
—
—
-$26M
—
$162M
Jun '21
—
-$26M
—
—
-$20M
—
$179M
Valuation over time
How the market has priced CRNX against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has fallen from 958.2× (Jan '24) to 479.6× (Jun '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is CRNX growing its revenue and profit?
Over the past 5 years, Crinetics Pharmaceuticals, Inc.'s revenue has grown 155.3% per year. These are computed facts, not advice.
How much debt does CRNX have?
As of FY2025, Crinetics Pharmaceuticals, Inc. reported — of total debt against $102M of cash.
What is CRNX's profit margin?
In FY2025, gross margin was 86.0%, operating margin -6714.8%, and net margin -6046.0%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.