7 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has declined 2.0% per year over the past 5 years.
Operating margin has contracted, at -1329.4% in the latest year.
Financial health
The company is unprofitable and has less than a year of cash runway at its current free-cash-flow burn.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
2025
$11M
-$148M
0.0%
-1329.4%
-121.2%
-84.5%
-$112M
—
$12M
2024
$10M
-$149M
0.0%
-1667.2%
-58.9%
-47.6%
-$143M
—
$16M
2023
$34M
-$102M
0.0%
-336.6%
-27.7%
-23.6%
-$105M
—
$51M
2022
$14M
-$99M
0.0%
-768.2%
-33.0%
-26.6%
-$97M
—
$58M
2021
$10M
-$67M
0.0%
-697.8%
-17.3%
-15.1%
-$35M
—
$240M
2020
$12M
-$34M
0.0%
-292.2%
146.4%
-95.2%
-$34M
—
$16M
2019
$6M
-$23M
0.0%
-592.7%
-314.0%
—
-$33M
—
$41M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Return on equity & assets (ROE / ROA)
ROEROA
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
ROE
ROA
FCF
Total debt
Cash
Jun '26
$1M
-$24M
0.0%
-1690.4%
-24.8%
-17.0%
-$23M
—
$26M
Mar '26
$2M
-$25M
0.0%
-1096.4%
-24.6%
-16.8%
-$27M
—
$12M
Dec '25
$4M
-$26M
0.0%
-722.0%
-21.7%
-15.1%
-$21M
—
$12M
Sep '25
$2M
-$28M
0.0%
-1337.6%
-19.4%
-14.1%
-$25M
—
$11M
Jun '25
$3M
-$54M
0.0%
-1784.0%
-32.6%
-24.5%
-$29M
—
$25M
Mar '25
$2M
-$40M
0.0%
-1823.8%
-18.4%
-14.6%
-$38M
—
$29M
Dec '24
$2M
-$35M
0.0%
-1871.7%
-14.0%
-11.3%
-$36M
—
$16M
Sep '24
$2M
-$35M
0.0%
-1889.2%
-12.3%
-10.1%
-$33M
—
$32M
Jun '24
$3M
-$38M
0.0%
-1255.8%
-12.1%
-10.1%
-$35M
—
$38M
Mar '24
$2M
-$41M
0.0%
-1893.9%
-12.0%
-10.1%
-$39M
—
$49M
Dec '23
$4M
-$35M
0.0%
-1052.3%
-9.4%
-8.0%
-$24M
—
$51M
Sep '23
$24M
-$10M
0.0%
-61.8%
-2.5%
-2.2%
-$34M
—
$104M
Jun '23
$4M
-$30M
0.0%
-875.3%
-11.0%
-8.4%
-$18M
—
$66M
Mar '23
$4M
-$28M
0.0%
-888.5%
-10.1%
-8.1%
-$30M
—
$53M
Dec '22
$4M
-$27M
0.0%
-828.2%
-9.0%
-7.2%
-$27M
—
$58M
Sep '22
$3M
-$27M
0.0%
-803.4%
-8.2%
-6.7%
-$24M
—
$82M
Jun '22
$4M
-$27M
0.0%
-678.2%
-7.7%
-6.3%
-$24M
—
$112M
Mar '22
$3M
-$19M
0.0%
-782.8%
-5.1%
-4.3%
-$22M
—
$148M
Dec '21
$3M
-$18M
0.0%
-797.4%
-4.8%
-4.2%
-$22M
—
$240M
Sep '21
$4M
-$21M
0.0%
-468.1%
-5.2%
-4.5%
-$16M
—
$435M
Valuation over time
How the market has priced CRBU against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-sales ratio has fallen from 41.2× (Mar '23) to 15.0× (Sep '26).
Price / sales (P/S)
P/S
Frequently asked questions
Is CRBU growing its revenue and profit?
Over the past 5 years, Caribou Biosciences, Inc.'s revenue has declined 2.0% per year. These are computed facts, not advice.
How much debt does CRBU have?
As of FY2025, Caribou Biosciences, Inc. reported — of total debt against $12M of cash.
What is CRBU's profit margin?
In FY2025, gross margin was —, operating margin -1329.4%, and net margin -1327.4%.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.