15 years of revenue, profit, cash flow and balance-sheet history through FY2025,
from SEC filings — with a computed, factual read of the trend.
Updated Overview →
Growth & profitability
Revenue has grown 117.9% per year over the past 5 years.
Operating margin has expanded, at 39.0% in the latest year.
Financial health
The company holds more cash ($90M) than total debt ($0).
Operating income covered interest expense 4.3× in the latest year.
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key annual figures
FY
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
2025
$875M
$264M
97.8%
39.0%
$345M
$0
$90M
2024
$451M
-$89M
97.3%
-0.6%
-$53M
$315M
$105M
2023
$331M
-$227M
98.6%
-31.3%
-$97M
$303M
$111M
2022
$271M
-$247M
97.6%
-54.8%
-$163M
$232M
$305M
2021
$157M
-$184M
95.4%
-113.1%
-$145M
$298M
$504M
2020
$18M
-$183M
91.3%
-981.1%
-$136M
$123M
$272M
2019
$49M
-$109M
92.4%
-203.7%
-$90M
$50M
$114M
2018
$21M
-$101M
0.0%
-456.2%
-$93M
$30M
$27M
2017
$25M
-$66M
95.5%
-227.9%
-$41M
$23M
$50M
2016
$26M
-$55M
91.3%
-184.4%
-$59M
$23M
$22M
2015
—
-$43M
—
—
-$18M
—
$29M
2014
—
-$45M
—
—
—
—
$55M
2013
—
-$30M
—
—
-$27M
—
$21M
2012
—
-$39M
—
—
-$38M
—
$21M
2011
—
-$57M
—
—
-$32M
—
$16M
Revenue & net income
RevenueNet income
Margins (gross / operating / net)
GrossOperatingNet
Free cash flow (CFO − capex, quarterly)
Free cash flow
Cash vs total debt
CashTotal debt
Cash flow: operating / investing / financing
OperatingInvestingFinancing
Key quarterly figures
Quarter
Revenue
Net income
Gross M
Op M
FCF
Total debt
Cash
Mar '26
$156M
-$722M
96.6%
-448.6%
-$62M
$395M
$172M
Dec '25
$407M
$246M
97.7%
64.0%
$291M
$0
$90M
Sep '25
$159M
$13M
98.6%
18.6%
$40M
$194M
$84M
Jun '25
$163M
$5M
98.3%
18.2%
$41M
$243M
$88M
Mar '25
$146M
$32000
96.9%
14.6%
-$28M
$315M
$105M
Dec '24
$132M
-$27M
95.4%
-3.4%
-$6M
$315M
$105M
Sep '24
$117M
-$14M
97.3%
6.6%
$8M
$314M
$97M
Jun '24
$109M
-$13M
98.4%
8.0%
-$2M
$314M
$78M
Mar '24
$93M
-$35M
98.6%
-15.6%
-$54M
$308M
$84M
Dec '23
$93M
-$62M
98.3%
-45.7%
-$9M
$303M
$111M
Sep '23
$87M
-$36M
98.7%
-13.7%
-$21M
$298M
$151M
Jun '23
$82M
-$75M
98.9%
-25.1%
-$19M
$293M
$146M
Mar '23
$69M
-$53M
98.6%
-41.3%
-$48M
$233M
$155M
Dec '22
$80M
-$72M
97.0%
-58.2%
-$24M
$232M
$305M
Sep '22
$76M
-$43M
95.3%
-23.0%
-$33M
$224M
$247M
Jun '22
$66M
-$59M
99.6%
-53.0%
-$28M
$145M
$273M
Mar '22
$50M
-$74M
99.5%
-100.1%
-$78M
$140M
$396M
Dec '21
$47M
-$18M
99.1%
-110.6%
-$34M
$298M
$504M
Sep '21
$41M
-$59M
98.6%
-108.8%
-$24M
$132M
$200M
Jun '21
$50M
-$43M
99.4%
-59.2%
-$26M
$127M
$210M
Valuation over time
How the market has priced BCRX against its own fundamentals since 2023-03 —
each month-end's share price set against the most recent annual filing, so the multiple moves
as price runs ahead of (or behind) earnings. Split-adjusted.
The price-to-earnings ratio has risen from 7.5× (Dec '25) to 9.5× (Jun '26).
The price-to-sales ratio has fallen from 7.8× (Mar '23) to 2.9× (Jun '26).
Price / earnings (P/E)
P/E
Price / sales (P/S)
P/S
Frequently asked questions
Is BCRX growing its revenue and profit?
Over the past 5 years, Biocryst Pharmaceuticals Inc's revenue has grown 117.9% per year. These are computed facts, not advice.
How much debt does BCRX have?
As of FY2025, Biocryst Pharmaceuticals Inc reported $0 of total debt against $90M of cash; operating income covered interest expense 4.3×.
What is BCRX's profit margin?
In FY2025, gross margin was 97.8%, operating margin 39.0%, and net margin 30.2%.
What is BCRX's P/E ratio?
As of Jun '26, Biocryst Pharmaceuticals Inc traded at a price-to-earnings ratio of about 9.5× (market cap ÷ latest annual net income). The valuation charts above show how its P/E, P/S have moved with the share price. These are computed facts, not advice.
Where does this data come from?
All figures are extracted from the company’s SEC EDGAR/XBRL filings — 10-K annual reports and 10-Q quarterly reports (use the Annual / Quarterly toggle). Quarterly figures are derived from the as-filed statements (year-to-date amounts are differenced into discrete quarters). Growth rates and ratios are computed by tradmap; nothing here is investment advice.
Source: SEC EDGAR / XBRL (10-K + 10-Q filings) · prices EOD (Databento), corporate-action-adjusted ·
growth rates, valuation multiples & ratios computed by tradmap. Valuation uses each month-end price
against the latest annual filing. Informational only — not investment advice.